1942-83-2

Basic information

• Product Name: Phosphine oxide, [1,1'-biphenyl]-4-yldiphenyl-
• CAS NO: 1942-83-2
• Molecular Formula: C24H19OP
• Molecular Weight: 354.388
• Mol File: 1942-83-2.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: Phosphine oxide, [1,1'-biphenyl]-4-yldiphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, [1,1'-biphenyl]-4-yldiphenyl-(1942-83-2)
• EPA Substance Registry System: Phosphine oxide, [1,1'-biphenyl]-4-yldiphenyl-(1942-83-2)

Safety Data

• Hazardous Substances Data: 1942-83-2(Hazardous Substances Data)

Usage

General Description

Phosphine oxide, [1,1'-biphenyl]-4-yldiphenyl- is a chemical compound that is commonly known as dibenzylphenylphosphine oxide. It is a type of organophosphorus compound with the molecular formula C26H21OP. Phosphine oxide, [1,1'-biphenyl]-4-yldiphenyl- is widely used as a ligand in organometallic chemistry and in the synthesis of various organic compounds. It is known for its ability to bind with metal atoms and has been used in the development of catalysts for a variety of chemical reactions. Additionally, it has potential applications in the pharmaceutical and agrochemical industries for the synthesis of biologically active compounds. However, it is important to handle this compound with care, as it can be toxic and may pose health risks if not used properly.

Upstream product

• 29712-10-5 tri([1,1′-biphenyl]-4-yl)bismuth 
• 4559-70-0 Diphenylphosphine oxide 
• 17763-78-9 4-phenylphenyl triflate 
• 92-69-3 4-Phenylphenol 
• 19813-76-4 4-phenylthioanisole 
• 92-52-4 biphenyl 
• 2920-38-9 4-cyano-1,1'-biphenyl 
• 719-80-2 Ethyl diphenylphosphinite 
• 1591-31-7 4-iodo-biphenyl 
• 5122-94-1 4-biphenylboronic acid 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 793-43-1 (4-Hydroxyphenyl)diphenylphosphine oxide 
• 673456-60-5 (4-trifluoromethylsulfonylphenyl)diphenylphosphine oxide 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

Palladium-Catalyzed C-P Bond-Forming Reactions of Aryl Nonaflates Accelerated by Iodide

An iodide-accelerated, palladium-catalyzed C-P bond-forming reaction of aryl nonaflates is described. The protocol was optimized for the synthesis of aryl phosphine oxides and was found to be tolerant of a wide range of aryl nonaflates. The general nature of this transformation was established with coupling to other P(O)H compounds for the synthesis of aryl phosphonates and an aryl phosphinate. The straightforward synthesis of stable, isolable aryl nonaflates, in combination with the rapid C-P bond-forming reaction allows facile preparation of aryl phosphorus target compounds from readily available phenol starting materials. The synthetic utility of this general strategy was demonstrated with the efficient preparation of an organic light-emitting diode (OLED) material and a phosphonophenylalanine mimic.

Phosphinylation of Non-activated Aryl Fluorides through Nucleophilic Aromatic Substitution at the Boundary of Concerted and Stepwise Mechanisms

Non-activated aryl fluorides reacted with potassium diorganophosphinites through a nucleophilic aromatic substitution (SNAr) reaction. Remarkably, both electron-neutral and electron-rich aryl fluorides participated in the reaction with substantially stabilized anionic P nucleophiles to form the corresponding tertiary phosphine oxides. Quantum chemical calculations suggested a nucleophile-dependent mechanism that involves both concerted and stepwise SNAr reaction pathways.

NiCl 2as a Cheap and Efficient Precatalyst for the Coupling of Aryl Fluorosulfonate and Phosphite/Phosphine Oxide

Herein, NiCl 2is employed as a cheap precatalyst in the formation of C(sp 2)-P bond via cross-coupling reaction of phenol derivatives and phosphine oxides/phosphites. This catalytic system allows a variety of phenols with diverse functional groups to transform into phosphates with good yields. No additional additive is used in this reaction.