194206-03-6

Basic information

• Product Name: methyl N²-(tert-butoxycarbonyl)-N⁵-phenyl-L-glutaminate
• Synonyms: methyl N²-(tert-butoxycarbonyl)-N⁵-phenyl-L-glutaminate
• CAS NO: 194206-03-6
• Molecular Weight: 336.388
• Mol File: 194206-03-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl N²-(tert-butoxycarbonyl)-N⁵-phenyl-L-glutaminate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N²-(tert-butoxycarbonyl)-N⁵-phenyl-L-glutaminate(194206-03-6)
• EPA Substance Registry System: methyl N²-(tert-butoxycarbonyl)-N⁵-phenyl-L-glutaminate(194206-03-6)

Safety Data

• Hazardous Substances Data: 194206-03-6(Hazardous Substances Data)

Upstream product

• 13574-13-5 Boc-Glu(OBzl)-OH 
• 72086-72-7 N-tert-butoxycarbonylglutamic acid methyl ester 
• 62-53-3 aniline 

Downstream Products

• 142166-24-3 methyl N^α-{1-[(2,4-diaminopteridin-6-yl)methyl]indolin-5-ylcarbonyl}-N^δ-phenyl-L-glutaminate 
• 142165-83-1 methyl N^α-[(1-benzyloxycarbonylindolin-5-yl)carbonyl]-N^δ-phenyl-L-glutaminate 
• 142165-84-2 (S)-2-[(2,3-Dihydro-1H-indole-5-carbonyl)-amino]-4-phenylcarbamoyl-butyric acid methyl ester 
• 194206-07-0 methyl N^δ-phenyl-L-glutaminate 

Relevant articles and documents

Synthesis of l -Kynurenine and Homo- l -Kynurenine via an Aza-Fries Rearrangement

l -Kynurenine, a non-proteinogenic amino acid, is the primary metabolite of tryptophan via the kynurenine pathway. Kynurenine is involved in a variety of biological processes occurring in the human body, notably in the central nervous system. Thus, the st

Antirheumatic agents. III. Novel methotrexate derivatives bearing an indoline ring and a modified ornithine or glutamie acid

The synthesis, biological profile and structure-activity relationship of various methotrexate (MTX) derivatives bearing an indoline ring are described. In particular, Nδ-(3-carboxyphenyl)-Nα-[1-[(2,4-diaminopteridin- 6-yl)methyl]indoline-5-ylcarbonyl]-L-glutamine (3d), compared to MTX; exhibited an enhanced anti-proliferative effect on human peripheral blood mononuclear cells obtained from healthy volunteers.