19432-61-2 Usage
Chemical class
Dihydropyridine derivative
Substituents
Benzyl group, cyano group
Attachment location
Pyridine ring
Potential use
Treatment of cardiovascular diseases (hypertension, angina)
Mechanism of action
Blocking calcium channels in smooth muscle cells
Effect
Vasodilation, lowering blood pressure
Implication
Possible development of calcium channel blockers and other pharmaceuticals targeting cardiovascular conditions
Research status
Further research needed to understand therapeutic potential and safety profile
Check Digit Verification of cas no
The CAS Registry Mumber 19432-61-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,3 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 19432-61:
(7*1)+(6*9)+(5*4)+(4*3)+(3*2)+(2*6)+(1*1)=112
112 % 10 = 2
So 19432-61-2 is a valid CAS Registry Number.
19432-61-2Relevant articles and documents
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Foster,Fyfe
, p. 1489 (1969)
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SUBSTITUENT EFFECT IN ADDITION OF CYANIDE ION TO p-SUBSTITUTED 1-BENZYL-3-CARBAMOYLPYRIDINIUM CHLORIDES
Pavlikova-Raclova, Frantiska,Kuthan, Josef
, p. 1401 - 1407 (2007/10/02)
The rate constants k2 and equilibrium constants K=k2/k-2 of the title process (A) have been measured in aqueous solutions of eight quaternary salts of nicotinamide I (R= p-XC6H4CH2) at 298 K.The substituent effects of X= CH3O, CH3, H, F, Cl, COOCH3, CN, and NO2 exhibiting the Hammett dependence have been correlated with half-wave potentials of reduction of the depolarizers I, and the correlation results have been discussed with respect to mechanism of the reaction (A).