194490-25-0 Usage
General Description
5-(Benzyloxy)-1H-indole-3-carbonitrile is a chemical compound with the molecular formula C18H13N2O. It is a derivative of indole, a heterocyclic organic compound, and is characterized by the presence of a benzyloxy group and a carbonitrile functional group. The compound has potential application in the field of medicinal chemistry and pharmaceuticals due to its structural features. Its unique chemical structure and potential biological activities make it an interesting target for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 194490-25-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,4,9 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 194490-25:
(8*1)+(7*9)+(6*4)+(5*4)+(4*9)+(3*0)+(2*2)+(1*5)=160
160 % 10 = 0
So 194490-25-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H12N2O/c17-9-13-10-18-16-7-6-14(8-15(13)16)19-11-12-4-2-1-3-5-12/h1-8,10,18H,11H2
194490-25-0Relevant articles and documents
Sodium bis(trimethylsilyl)amide in the oxidative conversion of aldehydes to nitriles
Jih, Ru Hwu,Fung, Fuh Wong
, p. 2513 - 2516 (2006)
The feasibility of the Me3Si species acting as a nucleofuge was investigated in compounds containing the NSiMe3 moiety. Treatment of various aromatic aldehydes with 2.2 equiv. of NaN(SiMe3)2 at 185°C in a sealed tube produced the corresponding nitriles in high yields (81-98%). In these reactions, NaN(SiMe3)2 acted as an oxidizing agent. Results from control experiments indicate that the Me 3Si unit can depart efficiently from the NSiMe3 moiety of N-silylimine intermediates. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
