194606-27-4

Basic information

• Product Name: Benzeneethanol, b-methyl-4-(2-methylpropyl)-, acetate, (S)-
• CAS NO: 194606-27-4
• Molecular Formula: C15H22O2
• Molecular Weight: 234.338
• Mol File: 194606-27-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzeneethanol, b-methyl-4-(2-methylpropyl)-, acetate, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, b-methyl-4-(2-methylpropyl)-, acetate, (S)-(194606-27-4)
• EPA Substance Registry System: Benzeneethanol, b-methyl-4-(2-methylpropyl)-, acetate, (S)-(194606-27-4)

Safety Data

• Hazardous Substances Data: 194606-27-4(Hazardous Substances Data)

Upstream product

• 108-05-4 vinyl acetate 
• 36039-36-8 2-(4-isobutylphenyl)propan-1-ol 
• 85609-09-2 1-iodo-4-isobutylbenzene 
• 194606-12-7 2-tert-butyl-4,5-dihydro-5-(4-isobutylphenyl)-1,3-dioxepin 
• 194606-19-4 (2R)-(+)-3-acetoxy-2-(4-isobutylphenyl)-1-propanol 
• 194606-25-2 Acetic acid (S)-2-(4-isobutyl-phenyl)-3-(toluene-4-sulfonyloxy)-propyl ester 
• 194606-15-0 2-(4-isobutylphenyl)-1,3-propanediol 
• 538-93-2 1-phenyl-2-methylpropane 

Downstream Products

• 114937-30-3 (2S)-2-<4-(2-Methylpropyl)phenyl>propan-1-ol 
• 51146-56-6 (S)-ibuprofen 

Relevant articles and documents

Lipase-mediated asymmetric construction of 2-arylpropionic acids: Enantiocontrolled syntheses of S-naproxen and S-ibuprofen

A general and enantiocontrolled synthetic route to 2-arylpropionic acids, represented by non-steroidal anti-inflammatory drugs S-naproxen 1a and S-ibuprofen 1b, has been developed by employing the lipase-mediated asymmetric acetylation of prochiral 2-aryl-1,3-propanediol 3, which has been derived via a Heck reaction, as the key step.