194718-56-4Relevant articles and documents
A convenient access to N,N-disubstituted amides derived from (1R,3S)-(-)-2,2-dimethyl-3-formylcyclopropane-1-carboxylic acid
Perollier, Celine,Pecaut, Jacques,Ramasseul, Rene,Marchon, Jean-Claude
, p. 517 - 524 (2007/10/03)
Enantiopure N,N-disubstituted amides are obtained in good yield from (1R,3S)-(-)-2,2-dimethyl-3-formylcyclopropane-1-carboxylic acid in three steps: dithiane protection of the aldehyde function; amidation of the carboxylic acid function; dethioketalizatio