194872-09-8

Basic information

• Product Name: 4-(methylsulfonylmethyl)piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 194872-09-8
• Molecular Weight: 277.385
• Mol File: 194872-09-8.mol
• Article Data: 4

Chemical Properties

• Density: 1.140
• CAS DataBase Reference: 4-(methylsulfonylmethyl)piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(methylsulfonylmethyl)piperidine-1-carboxylic acid tert-butyl ester(194872-09-8)
• EPA Substance Registry System: 4-(methylsulfonylmethyl)piperidine-1-carboxylic acid tert-butyl ester(194872-09-8)

Safety Data

• Hazardous Substances Data: 194872-09-8(Hazardous Substances Data)

Upstream product

• 166815-96-9 N-tert-butoxycarbonyl-4-(4-toluenesulphonyloxymethyl)piperidine 
• 123855-51-6 tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate 
• 161975-39-9 tert-butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate 
• 6457-49-4 4-piperidinemethanol 
• 124-63-0 methanesulfonyl chloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 597563-38-7 4-(methylthiomethyl)piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 597563-39-8 4-methanesulfonylmethyl-piperidine hydrochloride 
• 1010113-01-5 tert-butyl 4-((6-(4-(methylsulfonyl)phenyl)pyridine-3-yloxy)methyl)piperidin-1-carboxylate 
• 290328-53-9 4-(methylsulfonylmethyl)piperidine 

Relevant articles and documents

ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS

The present invention relates to a compound represented by formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

PIPERIDINE DERIVATIVES FOR G PR119 AGONIST

The present invention relates to novel piperidine derivatives, stereoisomers thereof or pharmaceutically acceptable salts thereof; methods for preparing the compound; and pharmaceutical compositions comprising the compound. The novel piperidine derivatives, according to the present invention, having an effect as GPR119 agonist can be used for treatment of metabolic disorders, including diabetes mellitus (especially type II) and related disorders