19490-87-0

Basic information

• Product Name: 7-METHOXY-2-METHYLQUINOLINE
• Synonyms: 7-METHOXY-2-METHYLQUINOLINE;2-Methyl-7-Methoxyquinoline
• CAS NO: 19490-87-0
• Molecular Formula: C₁₁H₁₁NO
• Molecular Weight: 173.21
• EINECS: -0
• Mol File: 19490-87-0.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 286.003°C at 760 mmHg
• Flash Point: 104.905°C
• Appearance: /
• Density: 1.103g/cm³
• Vapor Pressure: 0.005mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 6.15±0.50(Predicted)
• CAS DataBase Reference: 7-METHOXY-2-METHYLQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHOXY-2-METHYLQUINOLINE(19490-87-0)
• EPA Substance Registry System: 7-METHOXY-2-METHYLQUINOLINE(19490-87-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 19490-87-0(Hazardous Substances Data)

Usage

General Description

7-Methoxy-2-methylquinoline is a chemical compound known for its antimicrobial and antifungal properties. It is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. 7-METHOXY-2-METHYLQUINOLINE has also been studied for its potential application in the development of new drugs for the treatment of diseases such as malaria and tuberculosis. Additionally, 7-Methoxy-2-methylquinoline has been found to possess antioxidant and anti-inflammatory properties, making it a potential candidate for the development of new therapeutic agents in the future.

InChI:InChI=1/C11H11NO/c1-8-3-4-9-5-6-10(13-2)7-11(9)12-8/h3-7H,1-2H3

Upstream product

• 4965-34-8 2-methyl-7-bromo-quinoline 
• 123-73-9 trans-Crotonaldehyde 
• 536-90-3 m-Anisidine 
• 75-07-0 acetaldehyde 
• 75896-68-3 4-chloro-7-methoxy-2-methylquinoline 
• 682350-96-5 7-methoxy-2-(methylthio)quinoline 
• 33240-22-1 (E)-3-(3-Methoxy-phenylamino)-but-2-enoic acid ethyl ester 
• 591-19-5 m-Bromoaniline 
• 165112-03-8 7-hydroxy-2-methylquinoline 
• 74-88-4 methyl iodide 
• 64-17-5 ethanol 
• 109-92-2 ethyl vinyl ether 
• 90-04-0 2-methoxy-phenylamine 
• 123-73-9 crotonaldehyde 

Downstream Products

• 165112-03-8 7-hydroxy-2-methylquinoline 
• 852402-75-6 (S)-7-methoxyquinoline-2-carboxylic acid (1-phenylethyl)amide 
• 852402-85-8 (2S,3'S)-7-methoxy-1,2,3,4-tetrahydroquinoline-2-carboxylic acid (1-phenylethyl)amide 
• 852402-80-3 (2R,3'S)-7-methoxy-1,2,3,4-tetrahydroquinoline-2-carboxylic acid (1-phenylethyl)amide 
• 852403-01-1 (4aR,1'S)-9-methoxy-3-(1-phenylethyl)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline 
• 852403-06-6 (4aS,1'S)-9-methoxy-3-(1-phenylethyl)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline 
• 852402-91-6 (4aR,1'S)-9-methoxy-3-(1-phenylethyl)-2,3,4,4a,5,6-hexahydropyrazino[1,2-a]quinolin-1-one 
• 852402-96-1 (4aS,1'S)-9-methoxy-3-(1-phenylethyl)-2,3,4,4a,5,6-hexahydropyrazino[1,2-a]quinolin-1-one 
• 852402-71-2 7-methoxyquinoline-2-carboxylic acid 
• 168083-32-7 3-(7-methoxy-2-quinolinylmethoxy)aniline 
• 1351944-61-0 (E)-7-methoxy-2-styrylquinoline 
• 1422841-41-5 C₂₆H₂₂N₄O₂ 
• 1422841-66-4 C₂₆H₂₂N₄O₂ 
• 1422841-48-2 C₂₆H₂₂N₄OS 

Relevant articles and documents

Photocatalytic Synthesis of Quinolines via Povarov Reaction under Oxidant-Free Conditions

We describe here an approach for synthesizing quinolines either from N-alkyl anilines or from anilines and aldehydes. A dual-catalyst system consisting of a photocatalyst and a proton reduction cocatalyst is employed. Without the use of any sacrificial ox

Synthesis and characterization of 8-aminoquinolines, substituted by electron donating groups, as high-affinity copper chelators for the treatment of Alzheimer's disease

The deregulation of copper homeostasis generates copper–amyloid aggregation and strongly participates in neuron damage in the brains of patients with Alzheimer's disease. Therefore, copper chelators able to regulate copper homeostasis should be considered

Traceless Directing-Group Strategy in the Ru-Catalyzed, Formal [3 + 3] Annulation of Anilines with Allyl Alcohols: A One-Pot, Domino Approach for the Synthesis of Quinolines

A unique, ruthenium-catalyzed, [3 + 3] annulation of anilines with allyl alcohols in the synthesis of substituted quinolines is reported. The method employs a traceless directing group strategy in the proximal C-H bond activation and represents a one-pot Domino synthesis of quinolines from anilines.