195257-60-4

Basic information

• Product Name: Oxirane, [2-[(4-methoxyphenyl)methoxy]ethyl]-, (2S)-
• CAS NO: 195257-60-4
• Molecular Formula: C12H16O3
• Molecular Weight: 208.257
• Mol File: 195257-60-4.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Oxirane, [2-[(4-methoxyphenyl)methoxy]ethyl]-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxirane, [2-[(4-methoxyphenyl)methoxy]ethyl]-, (2S)-(195257-60-4)
• EPA Substance Registry System: Oxirane, [2-[(4-methoxyphenyl)methoxy]ethyl]-, (2S)-(195257-60-4)

Safety Data

• Hazardous Substances Data: 195257-60-4(Hazardous Substances Data)

Upstream product

• 142860-83-1 1-(4-methoxybenzyloxy)-3-butene 
• 119649-27-3 4-((4-methoxybenzyl)oxy)butanal 
• 1460293-40-6 (S)-2,2-diethyl-4-(2-(4-methoxybenzyloxy)ethyl)-1,3-dioxolane 
• 2746-25-0 p-Methoxybenzyl bromide 
• 142860-84-2 4-(p-methoxybenzyloxy)-1,2-epoxybutane 
• 824-94-2 p-methoxybenzyl chloride 
• 195257-54-6 (4S)-4-(2-[(4-methoxybenzyl)oxy]ethyl)-2,2-dimethyl-1,3-dioxolane 
• 193416-58-9 (2S)-4-[(4-methoxybenzyl)oxy]butane-1,2-diol 
• 209345-98-2 Methanesulfonic acid (S)-2-hydroxy-4-(4-methoxy-benzyloxy)-butyl ester 
• 195257-57-9 (S)-2-hydroxy-4-(4-methoxybenzyloxy)butyl 2,4,6-triisopropylbenzenesulfonate 
• 87018-31-3 (S)-2-bromo-(1,4)-butanediol 

Downstream Products

• 192047-43-1 (2R)-1-benzyloxy-3-{2-[(2R)-3-benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-propyl]-[1,3]dithian-2-yl}-propan-2-ol 
• 195257-61-5 (R)-1-(4-Methoxy-benzyloxy)-hex-5-yn-3-ol 
• 628316-30-3 (R)-1-O-p-methoxybenzyloctadec-17-ene-1,3-diol 
• 639087-21-1 (2S)-4-(p-methoxybenzyloxy)-1-[2-[2-(triisopropylsilanyloxy)ethyl][1,3]dithian-2-yl]butan-2-ol 
• 713143-76-1 (3R,5R/S)-1-(4-methoxy-benzyloxy)-5-methyl-hept-6-en-3-ol 
• 713143-73-8 (S)-{1-[2-(4-methoxy-benzyloxy)-ethyl]-3-methyl-but-3-enyloxy}-triethylsilane 
• 713143-75-0 Triethyl-{(R)-1-[2-(4-methoxy-benzyloxy)-ethyl]-3-methyl-pent-4-enyloxy}-silane 
• 713143-74-9 (R)-6-(4-Methoxy-benzyloxy)-2-methyl-4-triethylsilanyloxy-hexan-1-ol 
• 713143-71-6 2-methylamino-3-phenyl-propionic acid 1-[2-(4-methoxybenzyloxy)-ethyl]-3-methyl-pent-4-enyl ester 
• 713143-77-2 2-(tert-butoxycarbonyl-methyl-amino)-(S)-3-phenyl-propionic acid 1-[2-(4-methoxybenzyloxy)-ethyl]-3-methyl-pent-4-enyl ester 
• 713143-98-7 2-(tert-butoxycarbonyl-methyl-amino)-(S)-3-phenyl-propionic acid 1-[2-(4-methoxybenzyloxy)-ethyl]-3-methyl-pent-4-enyl ester 
• 761445-30-1 (2S,3R,5S)-1-Chloro-5-methoxy-7-(4-methoxy-benzyloxy)-heptane-2,3-diol 
• 639087-15-3 {(4R,6S)-6-[2-(p-methoxybenzyloxy)ethyl]-2,2-dimethyl[1,3]dioxan-4-yl}acetaldehyde 
• 639087-25-5 2-{(4R,6S)-6-[2-(p-methoxybenzyloxy)ethyl]-2,2-dimethyl[1,3]dioxan-4-yl}ethanol 

Relevant articles and documents

IMMUNOMODULATORY GLYCOSPHINGOLIPIDS AND METHODS OF USE THEREOF

Provided herein are a subset of alpha-galactosylceramide (alpha-GC) compounds having improved immunomodulatory activity, particularly with respect to NKT cell number and activity. Also provided herein are methods of use of such compounds, including in the modulation of NKT cells and/or activity in vivo. Further provided are combinatorial synthesis methods for generating alpha-GC compounds of specifically defined structure and thereby generating pure preparations thereof.

Synthesis of Ophiocerins A, B and C, Botryolide E, Decarestrictine O, Stagonolide C and 9-epi-Stagonolide C Employing Chiral Hexane-1,2,3,5-tetraol Derivatives as Building Blocks

An organocatalytic approach to the synthesis of (2R,3S)-hexane-1,2,3,5-tetraol (11) derivatives (in the forms of different stereoisomers and bearing different protecting groups) has been developed. The key chiral intermediates 11 were prepared with complete stereocontrol through the proline-catalyzed intermolecular aldol reaction between acetone and d-glyceraldehyde acetonide. The synthetic utility of the intermediates was demonstrated by their transformation into the title hydroxylated pyrans and a variety of unsaturated lactones through standard synthetic protocols.

SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS

In one aspect, the present invention provides novel derivatives of Δ12-PGJ3 and modular synthetic pathways to obtaining Δ12-PGJ3 and derivatives thereof. In some aspects, the present derivatives of Δ12-PGJ3 are useful as chemotherapeutic agents. The present disclosure also describes compositions of these derivatives as well as methods of use of the derivatives thereof.