19547-88-7 Usage
Description
L-Cysteine, N-acetyl-,methyl ester, acetate (ester) (9CI) is a derivative of the amino acid L-cysteine, which has been modified with an N-acetyl group and a methyl ester group. L-Cysteine, N-acetyl-,methyl ester, acetate (ester) (9CI) is also known as Mucothiol and has been found to possess NDM-1 inhibition activity. It is a promising candidate for various applications in different industries due to its unique properties.
Uses
Used in Pharmaceutical Industry:
L-Cysteine, N-acetyl-,methyl ester, acetate (ester) (9CI) is used as a pharmaceutical agent for its NDM-1 inhibition activity. This makes it a potential candidate for the development of new drugs targeting NDM-1 enzymes, which are associated with antibiotic resistance in bacteria.
Used in Addiction Treatment:
L-Cysteine, N-acetyl-,methyl ester, acetate (ester) (9CI) is used as a therapeutic agent for reducing the relapse of addictive behavior. Its potential in this area has been researched, and it may offer a new approach to managing addiction and promoting recovery.
Check Digit Verification of cas no
The CAS Registry Mumber 19547-88-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,5,4 and 7 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19547-88:
(7*1)+(6*9)+(5*5)+(4*4)+(3*7)+(2*8)+(1*8)=147
147 % 10 = 7
So 19547-88-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H13NO4S/c1-5(10)9-7(8(12)13-3)4-14-6(2)11/h7H,4H2,1-3H3,(H,9,10)/t7-/m0/s1
19547-88-7Relevant articles and documents
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Moss,R.A. et al.
, p. 5920 - 5927 (1978)
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Chemoselective Synthesis of N-Terminal Cysteinyl Thioesters via β,γ-C,S Thiol-Michael Addition
Petracca, Rita,Bowen, Katherine A.,McSweeney, Lauren,O'Flaherty, Siobhan,Genna, Vito,Twamley, Brendan,Devocelle, Marc,Scanlan, Eoin M.
supporting information, p. 3281 - 3285 (2019/05/10)
Dehydroalanine (ΔAla) is a highly electrophilic residue that can react efficiently with sulfur nucleophiles to furnish cysteinyl analogues. Herein, we report an efficient synthesis of N-terminal cysteinyl thioesters, suitable for S,N-acyl transfer, based on β,γ-C,S thiol-Michael addition. Both ionic and radical-based methodologies were found to be efficient for this process.
