195618-53-2

Basic information

• Product Name: N-{(R)-2-[2-(Adamantan-2-yloxycarbonylamino)-3-(5-fluoro-1H-indol-3-yl)-propionylamino]-1-phenyl-ethyl}-succinamic acid benzyl ester
• Synonyms: N-{(R)-2-[2-(Adamantan-2-yloxycarbonylamino)-3-(5-fluoro-1H-indol-3-yl)-propionylamino]-1-phenyl-ethyl}-succinamic acid benzyl ester
• CAS NO: 195618-53-2
• Molecular Weight: 708.83
• Mol File: 195618-53-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{(R)-2-[2-(Adamantan-2-yloxycarbonylamino)-3-(5-fluoro-1H-indol-3-yl)-propionylamino]-1-phenyl-ethyl}-succinamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-{(R)-2-[2-(Adamantan-2-yloxycarbonylamino)-3-(5-fluoro-1H-indol-3-yl)-propionylamino]-1-phenyl-ethyl}-succinamic acid benzyl ester(195618-53-2)
• EPA Substance Registry System: N-{(R)-2-[2-(Adamantan-2-yloxycarbonylamino)-3-(5-fluoro-1H-indol-3-yl)-propionylamino]-1-phenyl-ethyl}-succinamic acid benzyl ester(195618-53-2)

Safety Data

• Hazardous Substances Data: 195618-53-2(Hazardous Substances Data)

Upstream product

• 171489-71-7 5-fluoro-DL-tryptophan 
• 154-08-5 DL-5-fluorotryptophan 

Relevant articles and documents

SAR study of the indole moiety of CI-988, a potent and selective CCK-B antagonist

Due to the interesting pharmacological activity observed for CI-988, a potent and selective CCK-B receptor antagonist, we have continued to study the SAR of this antagonist. This particular study examines the importance of the indole moiety for binding affinity. The synthesis and receptor binding affinity for analogs containing functionalized indole derivatives and replacing the indole with various heterocycles are reported.