19572-10-2

Basic information

• Product Name: ethyl 8-ethyl-5,8-dihydro-2-methoxy-5-oxopyrido[2,3-d]pyrimidine-6-carboxylate
• Synonyms: ethyl 8-ethyl-5,8-dihydro-2-methoxy-5-oxopyrido[2,3-d]pyrimidine-6-carboxylate;8-Ethyl-5,8-dihydro-2-methoxy-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester;Einecs 243-164-0
• CAS NO: 19572-10-2
• Molecular Formula: C₁₃H₁₅N₃O₄
• Molecular Weight: 277.2759
• EINECS: 243-164-0
• Mol File: 19572-10-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 425.8°Cat760mmHg
• Flash Point: 211.3°C
• Appearance: /
• Density: 1.276g/cm³
• Vapor Pressure: 1.87E-07mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: ethyl 8-ethyl-5,8-dihydro-2-methoxy-5-oxopyrido[2,3-d]pyrimidine-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 8-ethyl-5,8-dihydro-2-methoxy-5-oxopyrido[2,3-d]pyrimidine-6-carboxylate(19572-10-2)
• EPA Substance Registry System: ethyl 8-ethyl-5,8-dihydro-2-methoxy-5-oxopyrido[2,3-d]pyrimidine-6-carboxylate(19572-10-2)

Safety Data

• Hazardous Substances Data: 19572-10-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H15N3O4/c1-4-16-7-9(12(18)20-5-2)10(17)8-6-14-13(19-3)15-11(8)16/h6-7H,4-5H2,1-3H3

Upstream product

• 65269-20-7 8-ethyl-2-methoxy-5-oxo-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester 

Downstream Products

• 33836-43-0 6-ethoxycarbonyl-8-ethyl-5-oxo-2-pyrrolidino-5,8-dihydro-pyrido[2,3-d]pyrimidine 

Relevant articles and documents

Process for the preparation of 4-chloro-5-alkoxycarbonyl-2-methoxy-pyrimidines

Process for the preparation of a 4-chloro-5-alkoxycarbonyl-2-methoxy-pyrimidine of the formula: STR1 IN WHICH R1 is a lower alkyl radical with 1 to 4 carbon atoms, which comprises the following stages: A) condensation of a salt of O-methylisourea and an inorganic or organic acid, with an alkyl alkoxymethylenemalonate STR2 in an aqueous medium and in the presence of an excess of an alkali metal hydroxide, to form the corresponding salt of the 5-alkoxycarbonyl-4-hydroxy-2-methoxy-pyrimidine, and neutralization of the said salt by the addition of an inorganic or organic acid, in order to liberate this 5-alkoxycarbonyl-4-hydroxy-2-methoxy-pyrimidine, and STR3 B) bringing the latter compound, suspended in dimethylformamide, into contact with thionyl chloride, at room temperature, in order to form the corresponding 4-chloro-5-alkoxycarbonyl-2-methoxy-pyrimidine: STR4