195730-68-8

Basic information

• Product Name: 1-methyl-2-(α-benzyloxybenzyl)benzimidazole
• Synonyms: 1-methyl-2-(α-benzyloxybenzyl)benzimidazole
• CAS NO: 195730-68-8
• Molecular Weight: 328.414
• Mol File: 195730-68-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methyl-2-(α-benzyloxybenzyl)benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-2-(α-benzyloxybenzyl)benzimidazole(195730-68-8)
• EPA Substance Registry System: 1-methyl-2-(α-benzyloxybenzyl)benzimidazole(195730-68-8)

Safety Data

• Hazardous Substances Data: 195730-68-8(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 17452-05-0 (1-methyl-1H-benzo[d]imidazol-2-yl)(phenyl)methanol 
• 100-52-7 benzaldehyde 
• 1632-83-3 1-Methylbenzimidazole 

Downstream Products

• 187336-09-0 1-(1-Methyl-1H-benzoimidazol-2-yl)-1,2-diphenyl-ethanol 

Relevant articles and documents

A new method of synthesizing deoxybenzoins from 1,3-dimethyl-2-(α- benzyloxybenzyl)imidazolium and 1,3-dimethyl-2-(α- benzyloxybenzyl)benzimidazolium iodides based on Wittig-type rearrangement

The treatment of 1,3-dimethyl-2-(α-benzyloxybenzyl)benzimidazolium iodides 1 with a base gave deoxybenzoins 2 in moderate yields. Sodium hydride (NaH), potassium carbonate (K2CO3), and cesium carbonate (Cs2CO3) were effective bases in this reaction. Deoxybenzoins 2 were produced through rearrangement of the benzyl group followed by expulsion of the 1,3- dimethylbenzimidazolium ylide (A). The rearrangement proceeds in a way similar to Wittig rearrangement. Deoxybenzoins 2 were also formed in good yields from 1,3-dimethyl-2-(α-benzyloxybenzyl)imidazolium iodides 4 upon similar treatment. However, the quaternary salts having a thiazolium moiety 5a and a pyridinium moiety 6a failed to produce deoxybenzoin (2a).