19581-24-9 Usage
Description
2-(4-nitrophenylthio)pyrimidine is a pyrimidine derivative with the molecular formula C10H7N3O2S, featuring a 4-nitrophenylthio group attached to the pyrimidine ring. This versatile chemical compound serves as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and has potential applications in the development of new drugs due to its ability to modulate biological processes. It has also been studied for its potential anti-inflammatory and anti-cancer properties.
Uses
Used in Pharmaceutical Industry:
2-(4-nitrophenylthio)pyrimidine is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs that can potentially treat a range of diseases and conditions.
Used in Agrochemical Industry:
In the agrochemical field, 2-(4-nitrophenylthio)pyrimidine is utilized as an intermediate in the production of agrochemicals, which can help in the development of more effective and targeted pesticides and other agricultural chemicals.
Used in Drug Development:
2-(4-nitrophenylthio)pyrimidine is employed as a key component in drug development, due to its potential to modulate biological processes. This makes it a valuable asset in the creation of innovative therapeutic agents.
Used in Anti-inflammatory and Anti-cancer Research:
2-(4-nitrophenylthio)pyrimidine is used as a subject of study in research aimed at discovering its potential anti-inflammatory and anti-cancer properties, which could lead to the development of new treatments for these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 19581-24-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,5,8 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19581-24:
(7*1)+(6*9)+(5*5)+(4*8)+(3*1)+(2*2)+(1*4)=129
129 % 10 = 9
So 19581-24-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H7N3O2S/c14-13(15)8-2-4-9(5-3-8)16-10-11-6-1-7-12-10/h1-7H
19581-24-9Relevant articles and documents
Facile aromatic nucleophilic substitution (SNAr) reactions in ionic liquids: An electrophile-nucleophile dual activation by [Omim]Br for the reaction
Zhang, Xiao,Lu, Guo-Ping,Cai, Chun
, p. 5580 - 5585 (2016/10/21)
A facile aromatic nucleophilic substitution (SNAr) reaction in recyclable [Omim]Br under relatively mild conditions has been described. An electrophile-nucleophile dual activation by [Omim]Br is also discovered based on control experiments, 1H NMR and IR spectroscopies. This chemistry provides an efficient and metal-free approach for the generation of Caryl-X (XS, N, O) bonds, many of which are significant synthetic intermediates or drugs, making this methodology attractive to both synthetic and medicinal chemistry.
Discovery of FR115092 : A novel antinephritic agent
Ogino, Takashi,Tsuji, Kiyoshi,Tojo, Takashi,Igari, Norihiro,Seki, Nobuo,Sudo, Yu,Manda, Toshitaka,Nishigaki, Fusako,Matsuo, Masaaki
, p. 75 - 80 (2007/10/03)
A series of dapsone-related 4-aminophenyl and 2-aminothiazolyl derivatives was prepared, and their antinephritic activity and blood toxicity were evaluated. 5-(2-Pyridylsulfonyl)-2-thiazolamine (FR115092,26) was effective against two nephritis models, namely graft-versus-host disease (GVHD) and autoimmune W/BF1 mice, and showed none of the blood toxicity observed with dapsone.
