195877-54-4

Basic information

• Product Name: (S)-1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE
• Synonyms: (S)-1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE;tert-Butyl 4-[(2S)-2-(benzyloxycarbonylamino)-3-methoxy-3-oxo-propyl]piperidine-1-carboxylate
• CAS NO: 195877-54-4
• Molecular Formula: C₂₂H₃₂N₂O₆
• Molecular Weight: 0
• Mol File: 195877-54-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE(195877-54-4)
• EPA Substance Registry System: (S)-1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE(195877-54-4)

Safety Data

• Hazardous Substances Data: 195877-54-4(Hazardous Substances Data)

Usage

Description

(S)-1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE is a piperidine derivative used in organic synthesis and medicinal chemistry. It features a BOC (tert-butoxycarbonyl) protecting group on the nitrogen atom and a CBZ (benzyloxycarbonyl) protecting group on the amino and methoxycarbonyl groups. These protecting groups are essential for masking reactive functional groups and preventing unwanted reactions, making the compound a valuable building block for synthesizing complex organic molecules.

Uses

Used in Pharmaceutical Industry:
(S)-1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure and versatile reactivity allow for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, (S)-1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE is used as a precursor for the synthesis of agrochemicals. Its protective groups facilitate the creation of compounds with specific properties, such as pest control or herbicidal activities.
Used in Organic Synthesis:
(S)-1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE is used as a building block in organic synthesis for the preparation of biologically active compounds. Its protective groups enable the synthesis of complex organic molecules with specific functionalities and properties.

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 195877-53-3 4-(2-amino-2-methoxycarbonyl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 1822-32-8 3-(4-piperidyl)propionic acid 
• 84228-93-3 3-(pyridin-4-yl)acrylic acid 
• 154775-43-6 3-(1-(tert-butoxycarbonyl)piperidin-4-yl)propanoic acid 
• 195877-50-0 S-2-azido-3-(N-Boc-piperidyl)-propionic acid 
• 195877-52-2 4-(2-azido-2-methoxycarbonyl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 195877-48-6 4-[3-(4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxo-propyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 195877-49-7 4-[(S)-2-Azido-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxo-propyl]-piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 195877-55-5 4-(2-benzyloxycarbonylamino-3-oxo-propyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 195877-57-7 4-(2-benzyloxycarbonylamino-3-hydroxy-3-methoxycarbonyl-propyl)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Compounds and Compositions as Channel Activating Protease Inhibitors

The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for, using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.