195877-59-9

Basic information

• Product Name: methyl (R)-2-((tert-butoxycarbonyl)amino)-3-cyclohexylpropanoate
• Synonyms: methyl (R)-2-((tert-butoxycarbonyl)amino)-3-cyclohexylpropanoate
• CAS NO: 195877-59-9
• Molecular Weight: 285.384
• Mol File: 195877-59-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (R)-2-((tert-butoxycarbonyl)amino)-3-cyclohexylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (R)-2-((tert-butoxycarbonyl)amino)-3-cyclohexylpropanoate(195877-59-9)
• EPA Substance Registry System: methyl (R)-2-((tert-butoxycarbonyl)amino)-3-cyclohexylpropanoate(195877-59-9)

Safety Data

• Hazardous Substances Data: 195877-59-9(Hazardous Substances Data)

Upstream product

• 127095-92-5 N-tert-butoxycarbonyl-D-cyclohexylalanine 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 

Downstream Products

• 769891-92-1 (R)-2-Amino-3-cyclohexyl-propionic acid methyl ester 
• 194985-18-7 C₃₆H₆₂N₆O₉ 
• 190904-23-5 {tert-Butoxycarbonyl-[(R)-2-cyclohexyl-1-(cyclopentyl-methoxycarbonylmethyl-carbamoyl)-ethyl]-amino}-acetic acid tert-butyl ester 
• 190904-25-7 {[(R)-2-(tert-Butoxycarbonyl-tert-butoxycarbonylmethyl-amino)-3-cyclohexyl-propionyl]-cyclopentyl-amino}-acetic acid 
• 190904-19-9 N-(tert-butyloxycarbonylmethyl)-N-Boc-D-Cha-OMe 
• 190904-21-3 (2R)-2-[(tert-butoxycarbonyl)(2-tert-butoxy-2-oxoethyl)amino]-3-cyclohexylpropanoic acid 

Relevant articles and documents

Novel acylguanidine containing thrombin inhibitors with reduced basicity at the P1 moiety

Replacement of the noragmatine group in thrombin inhibitors with a β- alanyl-guanidine group resulted in a nearly equipotent and more selective compound 8 despite the fact that the pK(a) of this P1 moiety is five orders of magnitude lower. Furt