19617-03-9

Basic information

• Product Name: (2E)-N-nitroso-3-phenyl-1,3-benzothiazol-2(3H)-imine
• CAS NO: 19617-03-9
• Molecular Formula: C₁₃H₉N₃OS
• Molecular Weight: 255.2951
• Mol File: 19617-03-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 414.2°C at 760 mmHg
• Flash Point: 204.3°C
• Density: 1.35g/cm³
• Vapor Pressure: 4.53E-07mmHg at 25°C
• Refractive Index: 1.709
• CAS DataBase Reference: (2E)-N-nitroso-3-phenyl-1,3-benzothiazol-2(3H)-imine(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-N-nitroso-3-phenyl-1,3-benzothiazol-2(3H)-imine(19617-03-9)
• EPA Substance Registry System: (2E)-N-nitroso-3-phenyl-1,3-benzothiazol-2(3H)-imine(19617-03-9)

Safety Data

• Hazardous Substances Data: 19617-03-9(Hazardous Substances Data)

Usage

Description

(2E)-N-nitroso-3-phenyl-1,3-benzothiazol-2(3H)-imine is a chemical compound that belongs to the class of nitroso compounds. It is known for its potential mutagenic and carcinogenic properties, making it a significant subject of study in laboratory research. (2E)-N-nitroso-3-phenyl-1,3-benzothiazol-2(3H)-imine's properties have implications for understanding the mechanisms of cancer and genetic mutations, as well as for developing safety measures in industrial applications.

Uses

Used in Laboratory Research:
(2E)-N-nitroso-3-phenyl-1,3-benzothiazol-2(3H)-imine is used as a research chemical for studying its effects on biological systems. It is particularly valuable in investigations related to cancer and genetic mutations, providing insights into the underlying mechanisms and potential countermeasures.
Used in Industrial Safety Measures:
Due to its potential hazards to human health and the environment, (2E)-N-nitroso-3-phenyl-1,3-benzothiazol-2(3H)-imine is also used in the development of safety protocols and guidelines for handling and disposing of this and similar compounds. This ensures that industries can manage risks associated with the use of such chemicals effectively.

Downstream Products

• 66179-79-1 2-(3-methyl-3H-benzothiazol-2-ylideneamino)-3-phenyl-benzothiazolium; chloride 
• 66179-81-5 bis-(3-phenyl-benzothiazol-2-yl)-azamethinium; chloride 
• 66221-73-6 tris-(3-phenyl-3H-benzothiazol-2-ylidene)-guanidinium; chloride 
• 54286-55-4 1,1'-diphenyl-3,3'-bis-(3-phenyl-3H-benzothiazol-2-ylidene)-1,1'-(2,2'-disulfanediyl-diphenyl)-bis-urea 
• 58177-05-2 3-phenyl-3H-benzothiazol-2-one dibutylhydrazone 
• 54287-75-1 2,2-dibutyl-3-phenyl-2,3-dihydro-benzothiazole 
• 58177-13-2 3-phenyl-3H-benzothiazol-2-one p-tolylhydrazone 
• 58177-12-1 3-phenyl-2,2-di-p-tolyl-2,3-dihydro-benzothiazole 
• 58190-24-2 2,2-dibenzyl-3-phenyl-2,3-dihydro-benzothiazole 
• 58190-26-4 benzaldehyde (3-phenyl-3H-benzothiazol-2-ylidene)-hydrazone 
• 58190-28-6 3-phenyl-3H-benzothiazol-2-one dibenzylhydrazone 
• 19617-06-2 Bis--disulfid 
• 51369-75-6 3-Phenyl-2,3-dihydrobenzothiazolon-azin 
• 66179-80-4 2-(3-ethyl-3H-benzothiazol-2-ylideneamino)-3-phenyl-benzothiazolium; chloride 

Relevant articles and documents

New NO-donors with antithrombotic and vasodilating activities, VIII: Benzothiazole-2(3H)-nitrosimines

Thirty title compounds were prepared and tested for their antiplatelet activity in the Born-test. Five nitrosimines inhibit the aggregation induced by collagen in concentrations below 10 μmol/L halfmaximally. Four compounds were investigated in an in vivo thrombosis model. An inhibition of thrombosis between 29 and 53% was observed in mesenteric arterioles of rats 2 h after p.o. administration (60 mg/kg). The effect in venoles was less pronounced (10-22%). For one compound these effects could still be demonstrated 4 h after oral application.