1962-27-2

Basic information

• Product Name: 1H-2-Benzopyran, 1-(4-chlorophenyl)-3,4-dihydro-
• CAS NO: 1962-27-2
• Molecular Formula: C15H13ClO
• Molecular Weight: 244.721
• Mol File: 1962-27-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-2-Benzopyran, 1-(4-chlorophenyl)-3,4-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzopyran, 1-(4-chlorophenyl)-3,4-dihydro-(1962-27-2)
• EPA Substance Registry System: 1H-2-Benzopyran, 1-(4-chlorophenyl)-3,4-dihydro-(1962-27-2)

Safety Data

• Hazardous Substances Data: 1962-27-2(Hazardous Substances Data)

Usage

Chemical class

Benzopyran derivatives

Substitution

1-(4-chlorophenyl) at the 1 position, 3,4-dihydroat the 3,4 positions of the benzopyran ring

Potential biological activities

Anti-inflammatory, neuroprotective, and antioxidant effects

Industrial use

Synthesis of various drugs

Research use

Medicinal chemistry research tool

Upstream product

• 493-05-0 isochromane 
• 7270-47-5 4-chlorophenylmagnesium iodide 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 60-12-8 2-phenylethanol 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 2029-70-1 2-(2-Bromaethyl)-4'-chlor-benzophenon 

Relevant articles and documents

Zeolite-catalyzed simple synthesis of isochromans via the oxa-Pictet-Spengler reaction

The synthesis of isochromans via oxa-Pictet-Spengler reaction using a modified small pore size zeolite E4 as catalyst was investigated. Ersorb-4 (E4) is a clinoptylolite-type zeolite material with high silicon content. The reaction of 2-phenylethanol deri

Organocatalytic approach for C(sp3)-H bond arylation, alkylation, and amidation of isochromans under facile conditions

A new catalytic approach for the synthesis of isochroman derivatives via direct C(sp3)-H bond arylation is described. The oxidation reaction with [bis(trifluoroacetoxy)iodo]benzene facilitates the regeneration of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone in the C(sp3)-H bond arylation of isochroman. The reaction conditions can also be used for alkyl Grignard reagents and amides to afford the corresponding isochroman derivatives.