196597-82-7Relevant articles and documents
Synthesis of a novel series of benzocycloalkene derivatives as melatonin receptor agonists
Fukatsu, Kohji,Uchikawa, Osamu,Kawada, Mitsuru,Yamano, Toru,Yamashita, Masayuki,Kato, Koki,Hirai, Keisuke,Hinuma, Shuji,Miyamoto, Masaomi,Ohkawa, Shigenori
, p. 4212 - 4221 (2007/10/03)
We synthesized a novel series of benzocycloalkene derivatives and evaluated their binding affinities to melatonin receptors. To control the spatial position of the amide group, one of the important pharmacophores, we incorporated an endo double bond, an e
Tricyclic compounds, their production and use
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, (2008/06/13)
A compound of the formula: STR1 wherein R1 is an optionally substituted hydrocarbon, amino or heterocyclic group; R2 is H or an optionally substituted hydrocarbon group; R3 is H or an optionally substituted hydrocarbon or heterocyclic group; X is CHR4, NR4, O or S in which R4 is H or an optionally substituted hydrocarbon group; Y is C, CH or N; ring A is optionally substituted 5- to 7-membered ring; ring B is an optionally substituted benzene ring; and m is 1 to 4, or a salt thereof, a process for producing it, an intermediate for the production and a pharmaceutical composition comprising it are provided.
