1967-99-3

Basic information

• Product Name: 3-methyl-4,5,6,7-tetrahydro-2H-indazole
• Synonyms: 1H-indazole, 4,5,6,7-tetrahydro-3-methyl-; 3-Methyl-4,5,6,7-tetrahydro-1H-indazole
• CAS NO: 1967-99-3
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.1943
• Mol File: 1967-99-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 300.2°C at 760 mmHg
• Flash Point: 140°C
• Density: 1.097g/cm³
• Vapor Pressure: 0.00203mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: 3-methyl-4,5,6,7-tetrahydro-2H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-4,5,6,7-tetrahydro-2H-indazole(1967-99-3)
• EPA Substance Registry System: 3-methyl-4,5,6,7-tetrahydro-2H-indazole(1967-99-3)

Safety Data

• Hazardous Substances Data: 1967-99-3(Hazardous Substances Data)

Usage

General Description

3-methyl-4,5,6,7-tetrahydro-2H-indazole, also known as Tetrahydroindazole, is a chemical compound belonging to the indazole class. It is a bicyclic heterocycle and a derivative of indazole. This chemical has a molecular formula of C9H13N and a molecular weight of 135.21 g/mol. It is commonly used as a building block in the synthesis of various pharmaceutical and agrochemical compounds. Tetrahydroindazole has also been studied for its potential biological activities, including its role as an anxiolytic agent in the treatment of anxiety disorders. Additionally, it has been investigated for its potential as a central nervous system stimulant and its activity in the cannabinoid receptors.

Upstream product

• 2214-01-9 3-methyl-3a,4,5,6,7,7a-hexahydro-1H-indazole 
• 874-23-7 2-acetylcyclohexanone 
• 75624-86-1 Triphenyl(4,5,6,7-tetrahydro-3-methyl-1H-indazol-7-yl)phosphonium-bromid 
• 75624-66-7 1-<2-Methoxy-3-(triphenylphosphoranyliden)-1-cyclohexen-1-yl>ethanon 
• 75624-74-7 (3-Acetyl-2-oxocyclohexyl)triphenylphosphonium-chlorid 
• 74581-96-7 (2-Methoxy-1-cyclohexen-1-yl)triphenylphosphonium-bromid 
• 931-49-7 1-ethenylcyclohexene 
• 932-66-1 1-cyclohexenyl methyl ketone 

Relevant articles and documents

Discovery of 3,3′-Spiro[Azetidine]-2-oxo-indoline Derivatives as Fusion Inhibitors for Treatment of RSV Infection

A new series of 3,3′-spirocyclic-2-oxo-indoline derivatives was synthesized and evaluated against respiratory syncytial virus (RSV) in a cell-based assay and animal model. Extensive structure-activity relationship study led to a lead compound 14h, which e

Gold-catalyzed hydroamination of alkynes and allenes with parent hydrazine

A diverse array of nitrogen-containing compounds were formed by the addition of hydrazine to alkynes, diynes, enynes, and allenes in the presence of cationic gold(I) complexes with a cyclic (alkyl)(amino)carbene ligand (see scheme; the X-ray crystal structure of the gold-hydrazine complex is shown). This hydroamination is an ideal initial step for the preparation of acyclic and heterocyclic bulk chemicals. Dipp=2,6-diisopropylphenyl. Copyright

Transformations of 4,9-Dimethyl-2,3,7,8-tetra-azatetracyclo4,1206,10>trideca-1,6-diene , a Bishydrazone having Two Bridgehead Double Bonds

Reduction of the anti-Bredt bishydrazone 4,9-dimethyl-2,3,7,8-tetra-azatetracyclo4,1206,10>trideca-1,6-diene with lithium aluminium hydride-aluminium chloride or by catalytic hydrogenation gives the bishydrazine 1,6-dimethyl-2,3,7,8-tetra-azatetracyclo4,1206,10>tridecane, but reaction with either lithium aluminium hydride or aluminium chloride gives dihydropyrazoles by ring cleavage.