196712-97-7

Basic information

• Product Name: 2-(4-dimethylaminobenzylidene)-1-azabicyclo[2.2.2]octan-3-one
• Synonyms: 2-(4-dimethylaminobenzylidene)-1-azabicyclo[2.2.2]octan-3-one
• CAS NO: 196712-97-7
• Molecular Weight: 256.348
• Mol File: 196712-97-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-dimethylaminobenzylidene)-1-azabicyclo[2.2.2]octan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-dimethylaminobenzylidene)-1-azabicyclo[2.2.2]octan-3-one(196712-97-7)
• EPA Substance Registry System: 2-(4-dimethylaminobenzylidene)-1-azabicyclo[2.2.2]octan-3-one(196712-97-7)

Safety Data

• Hazardous Substances Data: 196712-97-7(Hazardous Substances Data)

Upstream product

• 1193-65-3 3-quinuclidinone hydrochloride 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 3731-38-2 3-Quinuclidinone 

Downstream Products

• 852476-86-9 2-(4-dimethylamino-benzyl)-1-aza-bicyclo[2.2.2]octan-3-one 

Relevant articles and documents

Synthetic entry to tricyclic and tetracyclic quinuclidine derivatives by cycloaddition and ring transformation

The (Z)-2-arylidene-quinuclidines 5-8 were synthesized. Their reaction with aliphatic dibasic functional reagents in both basic and acidic conditions afforded the fused heterocycles 9, 10 and 11. However, the reaction of arylidene derivative 5 with an aromatic dibasic functional reagent gave benzimidazole 13 in lieu of the anticipated tetracyclic system, quinuclidino[3,2-e]benzo[b]-1,4- diazepine 12. Cycloadditions of 5 with different reagents gave the heterocyclic derivatives 17, 19, 22 and 23. Acid-catalyzed cyclization of 5 with excess resorcinol gave 24. Compounds 9a, 19 and 24 showed antibacterial activities.

Search for NO donors. Part I. 3-quinuclidone oximes

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