19690-01-8

Basic information

• Product Name: 1,2-diphenylethanone O-acetyl oxime
• Synonyms: 1,2-diphenylethanone O-acetyl oxime
• CAS NO: 19690-01-8
• Molecular Weight: 253.301
• Mol File: 19690-01-8.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1,2-diphenylethanone O-acetyl oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-diphenylethanone O-acetyl oxime(19690-01-8)
• EPA Substance Registry System: 1,2-diphenylethanone O-acetyl oxime(19690-01-8)

Safety Data

• Hazardous Substances Data: 19690-01-8(Hazardous Substances Data)

Upstream product

• 952-06-7 deoxybenzoin oxime 
• 75-36-5 acetyl chloride 
• 451-40-1 phenyl benzyl ketone 
• 108-24-7 acetic anhydride 

Downstream Products

• 3263-79-4 2,3,4,5-tetraphenyl-1H-pyrrole 
• 54605-79-7 2-hydroxy-2,4,5-triphenyl-1H-pyrrol-3(2H)-one 
• 886-66-8 1,4-diphenyl-1,3-butadiyne 
• 22514-82-5 2,3-diphenyl quinoline 
• 25922-93-4 4,5-diphenylpyrimidine 
• 104332-53-8 2,3-diphenyl-4(H)-oxofuro<3,2-c><1>benzopyran 
• 16483-98-0 2,3-diphenyl-2H-azirine 
• 30081-50-6 2,3-diphenylquinoline-4-carboxamide 
• 18411-23-9 4,5-diphenyl-2-(p-tolyl)-2H-1,2,3-triazole 

Relevant articles and documents

The organocatalytic enantiodivergent fluorination of β-ketodiaryl-phosphine oxides for the construction of carbon-fluorine quaternary stereocenters

Commercially available cinchona alkaloids that can catalyze the enantiodivergent fluorination of β-ketodiarylphosphine oxides were developed to construct carbon-fluorine quaternary stereocenters. This protocol features a wide scope of substrates and excellent enantioselectivities, and it is scalable.

Access to pyrrolo[2,1-: A] isoindolediones from oxime acetates and ninhydrin via Cu(i)-mediated domino annulations

A copper-mediated domino condensation reaction of readily accessible oxime acetates with ninhydrin is reported to afford pyrrolo[2,1-a]isoindolediones via new C-C & C-N bond formations. A wide range of oxime acetates were shown to generally participate in the reaction to produce the condensed products in excellent yields. The necessary control experiments were performed and the mechanism is proposed to involve sequentially the formation of iminium radical via Cu-mediated N-O bond cleavage of oxime acetates, addition of the radical to ninhydrin and rearrangement via ring expansion.

Catalyst free synthesis of mono- and disubstituted pyrimidines from O-acyl oximes

Transition-metal or iodine catalyzed transformations of O-acyl oximes to various N-heterocycles are well established. Herein, we report a catalyst free, oxime carboxylate based, three-component condensation method to access mono- and disubstituted pyrimidines. A broad range of substituted pyrimidines were prepared in moderate to excellent yields. Control experiments reveal that in situ generated formamidine is the key intermediate.