197093-16-6

Basic information

• Product Name: N-tosyl-N-propargylhydrazine
• Synonyms: N-tosyl-N-propargylhydrazine
• CAS NO: 197093-16-6
• Molecular Weight: 224.283
• Mol File: 197093-16-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-tosyl-N-propargylhydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: N-tosyl-N-propargylhydrazine(197093-16-6)
• EPA Substance Registry System: N-tosyl-N-propargylhydrazine(197093-16-6)

Safety Data

• Hazardous Substances Data: 197093-16-6(Hazardous Substances Data)

Upstream product

• 106-96-7 propargyl bromide 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 197093-33-7 3-phenyl-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-pyrazole 
• 73130-06-0 3-phenyl-1-(toluene-4-sulfonyl)-1H-pyrazole 
• 197093-23-5 3-(1H-pyrazol-3-yl)benzenemethanol 
• 149739-48-0 3-(3-(trifluoromethyl)phenyl)-1H-pyrazole 
• 149739-32-2 3-(2-fluorophenyl)-1H-pyrazole 
• 149739-61-7 3-(3-fluorophenyl)-1H-pyrazole 
• 27069-17-6 3-p-methoxyphenylpyrazole 
• 59843-75-3 3-p-tolyl-1H-pyrazole 
• 59843-77-5 1-(1H-pyrazol-3-yl)-3-nitrobenzene 
• 197093-31-5 N-tosyl-N-(1-phenyl-1-propyn-3-yl)hydrazine 
• 2458-26-6 3-phenylpyrazole 
• 20583-31-7 3-(4-nitrophenyl)-1H-pyrazole 

Relevant articles and documents

Functionalised Pyrazoles through a Facile One-Pot Procedure from N-Tosyl-N-propargylhydrazine and Aryl Iodides or Vinyl Triflates

Functionalised pyrazoles have been prepared in good overall yield through a facile one-pot procedure. The synthesis includes the palladium-catalysed coupling of the readily available N-tosyl-N-propargylhydrazine with aryl iodides or vinyl triflates, the palladium-catalysed annulation of the resulting N-tosyl-N-(1-aryl/vinyl-1-propyn3-yl)hydrazine and exposure of the reaction mixture arising from the annulation step to KOBut.