197159-55-0

Basic information

• Product Name: (S)-α-tert-butoxycarbonylamino-β-(2-methylthio-6-phenylpyrimidin-4-yl)propanoic acid α-tert-butyl ester
• Synonyms: (S)-α-tert-butoxycarbonylamino-β-(2-methylthio-6-phenylpyrimidin-4-yl)propanoic acid α-tert-butyl ester
• CAS NO: 197159-55-0
• Molecular Weight: 445.583
• Mol File: 197159-55-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-α-tert-butoxycarbonylamino-β-(2-methylthio-6-phenylpyrimidin-4-yl)propanoic acid α-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-α-tert-butoxycarbonylamino-β-(2-methylthio-6-phenylpyrimidin-4-yl)propanoic acid α-tert-butyl ester(197159-55-0)
• EPA Substance Registry System: (S)-α-tert-butoxycarbonylamino-β-(2-methylthio-6-phenylpyrimidin-4-yl)propanoic acid α-tert-butyl ester(197159-55-0)

Safety Data

• Hazardous Substances Data: 197159-55-0(Hazardous Substances Data)

Upstream product

• 53114-57-1 S-methylisothiourea hydrochloride 
• 197159-33-4 (S)-2-tert-butoxycarbonylamino-4-oxo-6-phenylhex-5-ynoic acid tert-butyl ester 
• 867-44-7 S-Methylisothiourea sulfate 
• 34582-32-6 N-tert-butoxycarbonyl aspartic acid tert-butyl ester 
• 122313-00-2 N-tert-butoxycarbonyl-L-aspartic acid α-tert-butyl ester β-N-methoxy-N-methylamide 

Downstream Products

• 197159-70-9 (S)-α-tert-butoxycarbonylamino-β-(2-methylsulfonyl-6-phenylpyrimidin-4-yl)propanoic acid α-tert-butyl ester 
• 197159-79-8 (S)-α-tert-butoxycarbonylamino-β-(2-amino-6-phenylpyrimidin-4-yl)propanoic acid α-tert-butyl ester 

Relevant articles and documents

The synthesis of pyrimidin-4-yI substituted a-amino acids. a versatile approach from alkynyl ketones

The reaction of amidines with a-amino acid alkynyl ketones is shown to be a versatile route to pyrimidin-4-yl substituted a-amino acids. This route is also applicable to a parallel synthesis approach and has allowed the formation of a range of pyrimidin-4-yl substituted a-amino acids, including the naturally occurring a-amino acid L-lathyrine 4.