197167-87-6

Basic information

• Product Name: (4S,6aS,9aR,9bS)-4,8-Diphenyl-hexahydro-pyrrolo[3',4':3,4]pyrrolo[2,1-c][1,4]oxazine-1,7,9-trione
• CAS NO: 197167-87-6
• Molecular Weight: 362.385
• Mol File: 197167-87-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (4S,6aS,9aR,9bS)-4,8-Diphenyl-hexahydro-pyrrolo[3',4':3,4]pyrrolo[2,1-c][1,4]oxazine-1,7,9-trione(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,6aS,9aR,9bS)-4,8-Diphenyl-hexahydro-pyrrolo[3',4':3,4]pyrrolo[2,1-c][1,4]oxazine-1,7,9-trione(197167-87-6)
• EPA Substance Registry System: (4S,6aS,9aR,9bS)-4,8-Diphenyl-hexahydro-pyrrolo[3',4':3,4]pyrrolo[2,1-c][1,4]oxazine-1,7,9-trione(197167-87-6)

Safety Data

• Hazardous Substances Data: 197167-87-6(Hazardous Substances Data)

Upstream product

• 197167-72-9 (5S)-N-(benzyloxycarbonylaminomethyl)-5-phenylmorpholin-2-one 
• 144896-92-4 (5S)-5-phenylmorpholin-2-one 
• 941-69-5 N-phenyl-maleimide 
• 412907-19-8 (5S)-N-(1'-benzotriazolylmethyl)-5-phenylmorpholin-2-one 
• 33797-51-2 eschenmoser's salt 
• 50-00-0 formaldehyd 

Relevant articles and documents

N-(1'-Benzotriazolylmethyl)-5-phenylmorpholin-2-one: A stable crystalline chiral azomethine ylid precursor

The crystalline adduct of (5S)-5-phenylmorpholin-2-one with formaldehyde and benzotriazole on treatment with acid generates an azomethine ylid which may be trapped with a range of dipolarophiles in yields superior to those using in situ generation methodology.

Development of a chiral stabilised azomethine ylid. A chiral relay system

The chiral, stabilised azomethine ylids (2) derived from (R)-2-phenylglycinol has been demonstrated to undergo enantioselective 1,3-dipolar cycloaddition reactions with a range of alkene and alkyne dipolarophiles.