197167-90-1

Basic information

• Product Name: (4S,6aS,9aR,9bS)-8-Methyl-4-phenyl-hexahydro-pyrrolo[3',4':3,4]pyrrolo[2,1-c][1,4]oxazine-1,7,9-trione
• CAS NO: 197167-90-1
• Molecular Weight: 300.314
• Mol File: 197167-90-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (4S,6aS,9aR,9bS)-8-Methyl-4-phenyl-hexahydro-pyrrolo[3',4':3,4]pyrrolo[2,1-c][1,4]oxazine-1,7,9-trione(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,6aS,9aR,9bS)-8-Methyl-4-phenyl-hexahydro-pyrrolo[3',4':3,4]pyrrolo[2,1-c][1,4]oxazine-1,7,9-trione(197167-90-1)
• EPA Substance Registry System: (4S,6aS,9aR,9bS)-8-Methyl-4-phenyl-hexahydro-pyrrolo[3',4':3,4]pyrrolo[2,1-c][1,4]oxazine-1,7,9-trione(197167-90-1)

Safety Data

• Hazardous Substances Data: 197167-90-1(Hazardous Substances Data)

Upstream product

• 930-88-1 N-methylmaleimide 
• 50-00-0 formaldehyd 
• 144896-92-4 (5S)-5-phenylmorpholin-2-one 
• 20989-17-7 (2S)-2-phenylglycinol 
• 197167-72-9 (5S)-N-(benzyloxycarbonylaminomethyl)-5-phenylmorpholin-2-one 
• 412907-19-8 (5S)-N-(1'-benzotriazolylmethyl)-5-phenylmorpholin-2-one 

Relevant articles and documents

N-(1'-Benzotriazolylmethyl)-5-phenylmorpholin-2-one: A stable crystalline chiral azomethine ylid precursor

The crystalline adduct of (5S)-5-phenylmorpholin-2-one with formaldehyde and benzotriazole on treatment with acid generates an azomethine ylid which may be trapped with a range of dipolarophiles in yields superior to those using in situ generation methodology.

Development of chiral stabilised azomethine ylids: A chiral memory relay system

Chiral, stabilised azomethine ylids incorporated in cyclic templates derived from (R)- or (S)-2-phenylglycinol and (S)-valine undergo enantioselective 1,3-dipolar cycloaddition reactions with a variety of dipolarophiles. Removal of the template in the cas