19726-10-4

Basic information

• Product Name: Phenol, 2-(1,5-diphenyl-1H-pyrazol-3-yl)-
• CAS NO: 19726-10-4
• Molecular Formula: C21H16N2O
• Molecular Weight: 312.371
• Mol File: 19726-10-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(1,5-diphenyl-1H-pyrazol-3-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(1,5-diphenyl-1H-pyrazol-3-yl)-(19726-10-4)
• EPA Substance Registry System: Phenol, 2-(1,5-diphenyl-1H-pyrazol-3-yl)-(19726-10-4)

Safety Data

• Hazardous Substances Data: 19726-10-4(Hazardous Substances Data)

Upstream product

• 1469-94-9 1-(2-hydroxyphenyl)-3-phenyl-1,3-propanedione 
• 100-63-0 phenylhydrazine 
• 6956-41-8 3-(2-hydroxyphenyl)-1,5-diphenyl-4,5-dihydropyrazole 
• 93-58-3 benzoic acid methyl ester 
• 7327-78-8 2-[1-(2-phenylhydrazino)ethyl]phenol 
• 118-93-4 o-hydroxyacetophenone 
• 487-26-3 Flavanone 
• 39729-11-8 2'-hydroxychalcone dibromides 
• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 100-52-7 benzaldehyde 
• 579-74-8 2-Methoxyacetophenone 
• 40524-62-7 1-(2-methoxyphenyl)-3-phenyl-2-propene-1-one 
• 95006-00-1 3-(2-methoxyphenyl)-1,5-diphenyl-2-pyrazoline 
• 1426534-15-7 3-(2-methoxyphenyl)-1,5-diphenyl-1H-pyrazole 

Downstream Products

• 1426533-83-6 C₂₂H₁₅F₃N₂O₃S 
• 1310361-44-4 C₃₁H₂₆N₂O₃ 
• 1310361-49-9 2-(2'-(1,5-diphenyl-1H-pyrazol-3-yl)biphenyl-3-yloxy)acetate acid 
• 1426533-90-5 4-(2-(1,5-diphenyl-1H-pyrazol-3-yl)phenoxy)butanoic acid 
• 1426533-91-6 C₂₆H₂₄N₂O₃ 

Relevant articles and documents

One-pot synthesis of 1,3,5-triarylpyrazoles

A series of novel 1,3,5-triarylpyrazoles were synthesized from flavanones, arylhydrazines, and trimethyl phosphate in an one-pot procedure. Facile reaction process, easy after-reaction workshop, and good yields are the distinct characteristics of the developed protocol. The target compounds were characterized by element analysis, infrared ray (IR), 1H NMR spectra, and electrospray ionization-mass spectrometry. The structure of representative compound (C23H20N2O3, Mr = 372.42) was further confirmed by X-ray diffraction. It crystallizes in monoclinic, space group P 21/c, a = 8.9720(5), b = 24.5523(13), c = 8.9687(6) A, α = 90.0000, β = 102.6417(17), γ = 90.0000°, V = 1927.76(20) A3, Z = 4, μ(MoKα) = 0.086, F(000) = 784, Dc = 1.283 g/cm3, the final R = 0.0349 and wR = 0.0844 for 1668 observed reflections (I > 2σ(I)).

Synthesis of pyrazole and isoxazole in triethanolamine medium

Reactions of 2′-hydroxy chalcone dibromides 2a-1 with phenyl hydrazine and hydrazine hydrate afford pyrazoles 1a-1 and with hydroxylamine hydrochloride give isoxazoles 5a-f in triethanolamine medium. Similarly reaction of β-diketone 3b-e with phenyl hydra

Lead Tetraacetate Oxidation of 1,3-Triaryl-5-hydroxyphenyl-pyrazolines

Lead tetraacetate oxidation of the title pyrazolines (Ia-d) leads to the pyrazoles (IIa-d) in which OH group in the 5-aryl moiety remains intact.Structures of pyrazoles (IIa-d) have been confirmed by elemental analyses and spectral data.