197302-33-3

Basic information

• Product Name: benzyl [(2R)-1-[methoxy(methyl)amino]-1-oxo-3-(phenylsulfanyl)-2-propanyl]carbamate
• Synonyms: benzyl [(2R)-1-[methoxy(methyl)amino]-1-oxo-3-(phenylsulfanyl)-2-propanyl]carbamate
• CAS NO: 197302-33-3
• Molecular Weight: 374.461
• Mol File: 197302-33-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: benzyl [(2R)-1-[methoxy(methyl)amino]-1-oxo-3-(phenylsulfanyl)-2-propanyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl [(2R)-1-[methoxy(methyl)amino]-1-oxo-3-(phenylsulfanyl)-2-propanyl]carbamate(197302-33-3)
• EPA Substance Registry System: benzyl [(2R)-1-[methoxy(methyl)amino]-1-oxo-3-(phenylsulfanyl)-2-propanyl]carbamate(197302-33-3)

Safety Data

• Hazardous Substances Data: 197302-33-3(Hazardous Substances Data)

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 82611-65-2 N-benzyloxycarbonyl-S-phenyl-L-cysteine 
• 684270-34-6 benzyl N-[(1S)-1-(hydroxymethyl)-2-[methoxy(methyl)amino]-2-oxo-ethyl]carbamate 
• 1145-80-8 N-(benzyloxycarbonyl)-L-serine 
• 930-69-8 sodium thiophenolate 
• 1117-97-1 N,0-dimethylhydroxylamine 

Downstream Products

• 1013401-21-2 (2R,3R)-3-amino-2-hydroxy-4-(phenylthio)butyric acid 
• 934020-92-5 (2-cyano-2-hydroxy-1-phenylsulfanylmethyl-ethyl)-carbamic acid benzyl ester 
• 934020-94-7 3-benzyloxycarbonylamino-2-hydroxy-4-phenylsulfanyl-butyric acid methyl ester 
• 934020-93-6 3-benzyloxycarbonylamino-2-hydroxy-4-phenylsulfanyl-butyric acid methyl ester 
• 159878-02-1 benzyl [(2R,3S)-4-chloro-3-hydroxy-1-(phenylsulfanyl)-2-butanyl]carbamate 
• 163462-16-6 benzyl [(1R)-1-[(2S)-2-oxiranyl]-2-(phenylsulfanyl)ethyl]carbamate 
• 194086-27-6 benzyl [(2R,3R)-4-chloro-3-hydroxy-1-(phenylsulfanyl)-2-butanyl]carbamate 
• 159878-01-0 (R)-(1-phenylthiomethyl-3-chloro-2-oxopropyl)carbamic acid benzyl ester 
• 159878-04-3 (3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-3-benzyloxycarbonylamino-2-hydroxy-4-(phenylthio)butyl]decahydroisoquinoline-3-carboxamide 
• 197302-36-6 (1S,2R)-2-[(benzyloxycarbonyl)amino]-1-[2-(1,3-dithianyl)]-3-(phenylthio)-1-propanol 
• 197302-37-7 ((1R,2S)-2-Hydroxy-3-oxo-1-phenylsulfanylmethyl-propyl)-carbamic acid benzyl ester 
• 934020-91-4 (1-formyl-2-phenylsulfanyl-ethyl)-carbamic acid benzyl ester 

Relevant articles and documents

Merging lithium carbenoid homologation and enzymatic reduction: A combinative approach to the HIV-protease inhibitor Nelfinavir

An effective stereocontrolled synthesis of the HIV protease inhibitor Nelfinavir is reported. Two transformations were identified crucial for achieving success: the formation of a densely functionalized α-chloroketone via the homologation of a Weinreb ami

Design and synthesis of BACE1 inhibitors containing a novel norstatine derivative (2R,3R)-3-amino-2-hydroxy-4-(phenylthio)butyric acid

A novel norstatine derivative, phenylthionorstatine [(2R,3R)-3-amino-2-hydroxy-4-(phenylthio)butyric acid; Ptns], containing a hydroxymethylcarbonyl (HMC) isostere was designed, synthesized, and stereochemically determined. Then, Ptns was introduced into