19740-90-0

Basic information

• Product Name: (1R,8S)-rel-9-Oxabicyclo[6.1.0]non-4-ene
• Synonyms: (1R,8S)-rel-9-Oxabicyclo[6.1.0]non-4-ene;1,2-Epoxy-cis-cyclooct-5-ene;5,6-Epoxy-cis-cyclooctene;5,6-Epoxycyclooctene
• CAS NO: 19740-90-0
• Molecular Formula: C₈H₁₂O
• Molecular Weight: 124.18
• Mol File: 19740-90-0.mol
• Article Data: 49

Chemical Properties

• Boiling Point: 178 ºC
• Flash Point: 54 ºC
• Appearance: /
• Density: 0.993
• Vapor Pressure: 1.36mmHg at 25°C
• Refractive Index: 1.49
• CAS DataBase Reference: (1R,8S)-rel-9-Oxabicyclo[6.1.0]non-4-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,8S)-rel-9-Oxabicyclo[6.1.0]non-4-ene(19740-90-0)
• EPA Substance Registry System: (1R,8S)-rel-9-Oxabicyclo[6.1.0]non-4-ene(19740-90-0)

Safety Data

• Hazardous Substances Data: 19740-90-0(Hazardous Substances Data)

Usage

Description

(1R,8S)-rel-9-Oxabicyclo[6.1.0]non-4-ene, also known as 1,8-Epoxy-p-menth-ene, is a bicyclic organic compound with the molecular formula C10H16O. It is a colorless liquid with a citrus-like odor and is commonly used in the fragrance and flavor industry.

Uses

Used in Fragrance and Flavor Industry:
(1R,8S)-rel-9-Oxabicyclo[6.1.0]non-4-ene is used as a fragrance and flavoring agent for its citrus-like odor and is commonly found in essential oils such as eucalyptus, citronella, and mint.
Used in Pharmaceutical Synthesis:
(1R,8S)-rel-9-Oxabicyclo[6.1.0]non-4-ene is used as a precursor in the synthesis of pharmaceuticals and other organic compounds.
Used in Natural Pesticides and Antibacterial Agents:
(1R,8S)-rel-9-Oxabicyclo[6.1.0]non-4-ene is used as an active ingredient in the development of natural pesticides and antibacterial agents due to its antimicrobial and insecticidal properties.

InChI:InChI=1/C8H12O/c1-2-4-6-8-7(9-8)5-3-1/h1-2,7-8H,3-6H2/b2-1-/t7-,8+

Upstream product

• 1552-12-1 1,5-cis,cis-cyclooctadiene 
• 108909-88-2 Trans-2-fluorocyclooct-5-en-1-ol 
• 93953-49-2 trans-8-iodo-cyclooct-4-en-1-yl acetate 
• 5259-72-3 cyclo-octa-1,5-diene 
• 931-88-4 1,2-cyclooctene 

Downstream Products

• 286-62-4 Cyclooctene oxide 
• 29417-19-4 trans-trans-2,5-di-iodo-9-oxabicyclo<4.2.1>nonane 
• 10299-46-4 endo,endo-2,6-diiodo-9-oxa-bicyclo[3.3.1]nonane 
• 51097-60-0 (Z)-oct-4-enedial 
• 4277-34-3 (Z)-cyclooct-4-enol 
• 108909-88-2 Trans-2-fluorocyclooct-5-en-1-ol 
• 123836-24-8 (+/-)-trans-8-phenyl-4-cycloocten-1-ol 
• 112348-22-8 (Z)-8-(benzylamino)cyclooct-4-enol 
• 292-64-8 Cyclooctan 
• 31598-91-1 rac-(Z)-cyclooct-5-en-1,2-diol 
• 801237-26-3 Acetic acid (2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-((Z)-8-benzyloxy-1-vinyl-deca-4,9-dienyloxy)-tetrahydro-pyran-3-yl ester 
• 203319-31-7 (Z)-(1R,2R)-cyclooct-5-ene-1,2-diol 
• 4277-32-1 (1S,2S)-cyclooctane-1,2-diol 
• 105282-65-3 N-benzyl-3-allyl-2-formyl-9-azabicyclo[4.2.1]nonane 

Relevant articles and documents

MONOACYLGLYCEROL LIPASE MODULATORS

Fused and bridged compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions: (I) wherein R1a, R1b, R2, and R3, are defined herein.

A Bioorthogonal Click Chemistry Toolbox for Targeted Synthesis of Branched and Well-Defined Protein–Protein Conjugates

Bioorthogonal chemistry holds great potential to generate difficult-to-access protein–protein conjugate architectures. Current applications are hampered by challenging protein expression systems, slow conjugation chemistry, use of undesirable catalysts, or often do not result in quantitative product formation. Here we present a highly efficient technology for protein functionalization with commonly used bioorthogonal motifs for Diels–Alder cycloaddition with inverse electron demand (DAinv). With the aim of precisely generating branched protein chimeras, we systematically assessed the reactivity, stability and side product formation of various bioorthogonal chemistries directly at the protein level. We demonstrate the efficiency and versatility of our conjugation platform using different functional proteins and the therapeutic antibody trastuzumab. This technology enables fast and routine access to tailored and hitherto inaccessible protein chimeras useful for a variety of scientific disciplines. We expect our work to substantially enhance antibody applications such as immunodetection and protein toxin-based targeted cancer therapies.

Synthesis of functionalized carbon microspheres and their catalyst activity in C—O and C—N bond formation reactions

Disclosed herein is a simple process for functionalization/grafting of carbon microspheres obtained from bagasse with various active functional groups onto it and use of the same as catalyst for various organic reactions, having very high selectivity and conversion rate.