19746-37-3 Usage
Description
BOC-CYS(ACM)-OH, also known as Boc-Cysteine Acetyl Mixed Anhydride, is a Cystine derivative characterized by its white powder form. It is a versatile compound used in various chemical synthesis and peptide chemistry due to its unique chemical properties.
Uses
Used in Chemical Synthesis:
BOC-CYS(ACM)-OH is used as a building block in chemical synthesis for the development of various pharmaceuticals and bioactive compounds. Its unique structure allows for the formation of stable bonds and the creation of complex molecules.
Used in Peptide Chemistry:
In peptide chemistry, BOC-CYS(ACM)-OH is used as a key component in the synthesis of peptides and proteins. Its reactivity and stability contribute to the formation of well-defined peptide sequences and the development of therapeutic peptides.
Used in Pharmaceutical Industry:
BOC-CYS(ACM)-OH is used as an intermediate in the production of pharmaceuticals, particularly in the synthesis of drugs targeting various diseases. Its versatility and compatibility with other chemical compounds make it a valuable asset in drug development.
Used in Biochemical Research:
In biochemical research, BOC-CYS(ACM)-OH is employed as a reagent for studying protein structure, function, and interactions. Its ability to form stable bonds with other molecules aids in the investigation of biological processes and the development of novel therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 19746-37-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,7,4 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 19746-37:
(7*1)+(6*9)+(5*7)+(4*4)+(3*6)+(2*3)+(1*7)=143
143 % 10 = 3
So 19746-37-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H20N2O5S/c1-7(14)12-6-19-5-8(9(15)16)13-10(17)18-11(2,3)4/h8H,5-6H2,1-4H3,(H,12,14)(H,13,17)(H,15,16)/t8-/m1/s1
19746-37-3Relevant articles and documents
A comprehensive one-pot synthesis of protected cysteine and selenocysteine SPPS derivatives
Flemer, Stevenson
, p. 1257 - 1264 (2015/04/14)
A proof-of-principle methodology is presented in which all commercially-available cysteine (Cys) and selenocysteine (Sec) solid phase peptide synthesis (SPPS) derivatives are synthesized in high yield from easily prepared protected dichalcogenide precursors. A Zn-mediated biphasic reduction process applied to a series of four bis-Nα-protected dichalcogenide compounds allows facile conversion to their corresponding thiol and selenol intermediates followed by insitu S- or Se-alkylation with various electrophiles to directly access twenty one known Cys and Sec SPPS derivatives. Most of these derivatives were able to be precipitated in crude form out of petroleum ether in sufficient purity for direct use as peptide building blocks. Subsequent incorporation of these derivatives into peptide models nicely illustrates their viability and applicability toward SPPS.
The synthesis of peptides in aqueous medium. IV. A novel protecting group for cysteine.
Veber,Milkowski,Denkewalter,Hirschmann
, p. 3057 - 3058 (2007/10/05)
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