197507-22-5 Usage
Description
METHYL 2-FLUORO-4-HYDROXYBENZOATE is an organic compound that serves as an intermediate in the synthesis of various compounds. It possesses the ability to inhibit cytosolic phospholipase A2α, making it a valuable component in the development of pharmaceuticals and other applications.
Uses
Used in Pharmaceutical Industry:
METHYL 2-FLUORO-4-HYDROXYBENZOATE is used as an intermediate in the synthesis of 3-(2-fluoro-4-hydroxyphenyl)-5-(trifluoromethyl)-4-isoxazolecarboxylic acid methyl ester (F591865), a compound with potential applications in the treatment of various diseases and conditions.
Used in Chemical Research:
METHYL 2-FLUORO-4-HYDROXYBENZOATE is used as a research compound for studying its properties and potential applications in various fields, including the development of new drugs and materials.
Used in Compound Preparation:
METHYL 2-FLUORO-4-HYDROXYBENZOATE is used in the preparation of compounds that can inhibit cytosolic phospholipase A2α, an enzyme involved in various inflammatory processes. This makes it a valuable component in the development of anti-inflammatory drugs and other therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 197507-22-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,5,0 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 197507-22:
(8*1)+(7*9)+(6*7)+(5*5)+(4*0)+(3*7)+(2*2)+(1*2)=165
165 % 10 = 5
So 197507-22-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H7FO3/c1-12-8(11)6-3-2-5(10)4-7(6)9/h2-4,10H,1H3
197507-22-5Relevant articles and documents
NOVEL COMPOUNDS FOR THE TREATMENT OF PARASITIC INFECTIONS
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Page/Page column 66, (2019/08/14)
The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding compositions, and methods and/or uses in therapy, for example in the treatment of parasitic infections such as malaria, in particular infection by
Synergistic Photo-Copper-Catalyzed Hydroxylation of (Hetero)aryl Halides with Molecular Oxygen
Zhang, Xin,Wu, Ge,Gao, Wenxia,Ding, Jinchang,Huang, Xiaobo,Liu, Miaochang,Wu, Huayue
supporting information, p. 708 - 711 (2018/02/09)
Photoredox-mediated copper-catalyzed hydroxylation of (hetero)aryl halides (including chlorides, bromides, and iodides) with O2 at room temperature has been developed. Preliminary mechanistic studies indicate no arylcopper intermediate and that aryl radicals are involved in this procedure. 18O-labeling experiments confirm the hydroxyl oxygen atom originated from molecular oxygen.
Synthesis and Structure-Activity Relationship Studies of Derivatives of the Dual Aromatase-Sulfatase Inhibitor 4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate
Woo, L. W. Lawrence,Wood, Paul M.,Bubert, Christian,Thomas, Mark P.,Purohit, Atul,Potter, Barry V. L.
, p. 779 - 799 (2013/08/25)
4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate and its ortho-halogenated (F, Cl, Br) derivatives are first-generation dual aromatase and sulfatase inhibitors (DASIs). Structure-activity relationship studies were performed on these