197978-61-3

Basic information

• Product Name: C₂₃H₂₄O₇
• CAS NO: 197978-61-3
• Molecular Weight: 412.439
• Mol File: 197978-61-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₄O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₄O₇(197978-61-3)
• EPA Substance Registry System: C₂₃H₂₄O₇(197978-61-3)

Safety Data

• Hazardous Substances Data: 197978-61-3(Hazardous Substances Data)

Upstream product

• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 
• 65859-90-7 dimethyl (E)-benzylidenesuccinate 

Relevant articles and documents

Synthesis and evaluation of 1,4-diphenylbutadiene derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) production

Butadiene-imide 1 (T-686) derivatives were synthesized and evaluated for their inhibitory activity against PAI-1 production and their ADMET (DMPK and toxicology) profiles. Among these derivatives, compound 15k (T-2639) showed good antithrombotic activity in two rat thrombosis models without affecting bleeding time, indicating reduction of haemorrhagic risk. We also describe in this report a practical synthesis of 15k suitable for scale-up using Z,E-selective Stobbe condensation.