19820-76-9Relevant articles and documents
Pyridyl-cyclopentadiene Re(CO)2+ complexes as a compact core system for SPECT ligand development
Ackroyd, Nathan C.,Katzenellenbogen, John A.
, p. 3669 - 3671 (2010)
An η1,η5-rhenium complex has been prepared, starting from a CpRe(CO)3 complex substituted with a pendant aromatic amine. This unique complex has potential application as a surrogate for a technetium-99m complex, a common radioisotope for biomedical imaging applications. Chelation occurred via photochemical decarbonylation of the rhenium, which opened a binding site for the aromatic amine.
Ion-Pair-Directed Borylation of Aromatic Phosphonium Salts
Lee, Bernadette,Mihai, Madalina T.,Stojalnikova, Violeta,Phipps, Robert J.
, p. 13124 - 13134 (2019/06/17)
Control of positional selectivity in C-H activation reactions remains a challenge for synthetic chemists. Noncovalent catalysis has the potential to be a powerful strategy to address this challenge. As a part of our ongoing investigations into the use of ion-pairing interactions in site-selective catalysis, we demonstrate that several classes of aromatic phosphonium salts undergo iridium-catalyzed C-H borylation with a high selectivity for the arene meta position. This is achieved using a bifunctional bipyridine ligand bearing a pendant sulfonate group, which had previously been successful for borylation of aromatic ammonium salts. In this case, the phosphonium salts give a higher meta selectivity than the corresponding ammonium salts. We propose that the high selectivity occurs due to an attractive electrostatic interaction between the substrate and the ligand in the transition state for borylation.
Metal-free C(sp3)-H bond sulfonyloxylation of 2-alkylpyridines and alkylnitrones
Wang, Chang-Sheng,Dixneuf, Pierre H.,Soulé, Jean-Fran?ois
supporting information, p. 4954 - 4957 (2018/07/25)
Pyridin-2-ylmethyl tosylate derivatives are obtained in high yields from 2-alkylpyridine 1-oxides via a [3,3]-sigmatropic rearrangement of the adduct between 2-alkylpridine 1-oxides with benzenesulfonyl chlorides. Moreover, alkylnitrones also undergo [3,3]-sigmatropic rearrangement to give α-tosylated ketones after hydrolysis. Substitution reactions with nucleophiles then lead to diverse useful functionalizations for the synthesis of pincer ligands.
