198217-02-6

Basic information

• Product Name: {3-[Benzoyloxy-((E)-oct-2-enoyl)-amino]-propyl}-carbamic acid tert-butyl ester
• CAS NO: 198217-02-6
• Molecular Weight: 418.533
• Mol File: 198217-02-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: {3-[Benzoyloxy-((E)-oct-2-enoyl)-amino]-propyl}-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {3-[Benzoyloxy-((E)-oct-2-enoyl)-amino]-propyl}-carbamic acid tert-butyl ester(198217-02-6)
• EPA Substance Registry System: {3-[Benzoyloxy-((E)-oct-2-enoyl)-amino]-propyl}-carbamic acid tert-butyl ester(198217-02-6)

Safety Data

• Hazardous Substances Data: 198217-02-6(Hazardous Substances Data)

Upstream product

• 100808-08-0 (E)-oct-2-enoic acid chloride 
• 75178-96-0 N-Boc-1,3-diaminopropane 
• 94-36-0 dibenzoyl peroxide 
• 198217-06-0 N^α-benzoyloxy-3-(tert-butoxycarbonylamino)propylamine 
• 1871-67-6 (E)-oct-2-enoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

Total synthesis of acinetoferrin

The total synthesis of a novel siderophore, acinetoferrin, is described. The key transformation involves the tandem oxidation and acylation of the N3-amino group of N1-BOC propane diamine prior to coupling with the external carboxyls of citric acid. A 'one-pot-two-step' reaction converted a primary amine (RNH2) into a O-benzoyl hydroxamate (i.e., RN(OOCPh)COR') in good yield (68%). These studies demonstrated the utility of the O-benzoyl protecting group in the synthesis of α,β-unsaturated hydroxamic acids.