19833-82-0Relevant articles and documents
First synthesis of N-(3-carboxylpropyl)-5-amino-2-hydroxy-3-tridecyl-1,4- benzoquinone, an unusual quinone isolated from Embelia ribes
McErlean, Christopher S. P.,Moody, Christopher J.
, p. 10298 - 10301 (2007)
(Chemical Equation Presented) The first synthesis of the unusual nitrogen-containing 3-alkyl-1,4-benzoquinone, N-(3-carboxylpropyl)-5-amino-2- hydroxy-3-tridecyl-1,4-benzoquinone, isolated from Embelia ribes, is reported. The key steps are a microwave-ass
Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes
Filosa, Rosanna,Peduto, Antonella,Schaible, Anja M.,Krauth, Verena,Weinigel, Christina,Barz, Dagmar,Petronzi, Carmen,Bruno, Ferdinando,Roviezzo, Fiorentina,Spaziano, Giuseppe,D'Agostino, Bruno,De Rosa, Mario,Werz, Oliver
, p. 132 - 139 (2015/04/14)
5-Lipoxygenase (5-LO) is a potential target for pharmacological intervention with various inflammatory and allergic diseases. Starting from the natural dual 5-LO/microsomal prostaglandin E2 synthase (mPGES)-1 inhibitor embelin (2,5-dihydroxy-3-
Synthesis and biological activities of N-(3-Carboxylpropyl)-5-amino-2- hydroxy-3-tridecyl-1,4-benzoquinone and analogues
Madathil, Manikandadas M.,Khdour, Omar M.,Jaruvangsanti, Jennifer,Hecht, Sidney M.
, p. 2209 - 2215 (2013/02/25)
The synthesis of benzoquinone natural product 2 and three analogues is described. The synthesized compounds were tested for their ability to protect Friedreich's ataxia (FRDA) lymphocytes from induced oxidative stress. One of the analogues (3) conferred c