1984-27-6

Basic information

• Product Name: 4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE
• Synonyms: 4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE;p-bromo-n-isopropyl-benzenesulfonamid;N-ISOPROPYL 4-BROMOBENZENESULFONAMIDE;4-Bromo-N-isopropylbenzenesulphonamide 98%;N-Isopropyl-p-bromobenzenesulfonamide;4-bromo-N-isopropyl-benzenesulfonamide;4-bromo-N-propan-2-ylbenzenesulfonamide;4-bromo-N-propan-2-yl-benzenesulfonamide
• CAS NO: 1984-27-6
• Molecular Formula: C₉H₁₂BrNO₂S
• Molecular Weight: 278.17
• Product Categories: blocks;Bromides;Sulfonamides
• Mol File: 1984-27-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 87-89
• Boiling Point: 348.4 °C at 760 mmHg
• Flash Point: 164.5 °C
• Appearance: /
• Density: 1.467 g/cm³
• Vapor Pressure: 5.05E-05mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 11.48±0.50(Predicted)
• CAS DataBase Reference: 4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE(1984-27-6)
• EPA Substance Registry System: 4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE(1984-27-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 1984-27-6(Hazardous Substances Data)

Usage

Description

4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE is a benzenesulfonamide derivative characterized by its chemical structure that features a bromine atom at the 4th position of the benzene ring and an isopropyl group attached to the nitrogen atom. 4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE is known for its potential applications in various industries, particularly in organic synthesis and pharmaceuticals.

Uses

Used in Organic Synthesis:
4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE is used as an intermediate in organic synthesis for the production of various chemical compounds. Its unique structure allows it to serve as a building block for the creation of more complex molecules, which can be further utilized in different applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE is used as an intermediate for the development of new drugs. Its chemical properties make it a valuable component in the synthesis of various pharmaceutical compounds, potentially leading to the discovery of novel therapeutic agents.
Used in Chemical Research:
4-BROMO-N-ISOPROPYLBENZENESULPHONAMIDE is also utilized in chemical research as a model compound for studying the properties and reactivity of benzenesulfonamide derivatives. This helps researchers gain a deeper understanding of the structure-activity relationships and the potential applications of similar compounds in various fields.

InChI:InChI=1/C9H12BrNO2S/c1-7(2)11-14(12,13)9-5-3-8(10)4-6-9/h3-7,11H,1-2H3

Upstream product

• 75-31-0 isopropylamine 
• 108-20-3 di-isopropyl ether 
• 701-34-8 4-bromo-benzenesulfonic acid amide 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 67-63-0 isopropyl alcohol 

Downstream Products

• 1572928-52-9 N-(1-methylethyl)-4-(2-(1-propyn-1-yl)-1-piperazinyl)benzenesulfonamide 
• 1572928-53-0 tert-butyl (5-((4-(4-((1-methylethyl)sulfamoyl)phenyl)-3-(1-propyn-1-yl)-1-piperazinyl)sulfonyl)-2-pyridinyl)carbamate 
• 1572927-77-5 4-(2S)-(4-((6-amino-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)-N-(1-methylethyl)benzenesulfonamide 
• 1572927-78-6 4-(2R)-(4-((6-amino-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)-N-(1-methylethyl)benzenesulfonamide 
• 1572928-51-8 benzyl 4-(4-((1-methylethyl)-sulfamoyl)phenyl)-3-(1-propyn-1-yl)-1-piperazinecarboxylate 
• 1572927-76-4 4-(4-((6-amino-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)-N-(1-methylethyl)benzenesulfonamide 

Relevant articles and documents

NOVEL COMPOUND HAVING BLT INHIBITORY ACTIVITY AND COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT

The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, comprising same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.

N-alkylation of sulfonamides with alcohols by Tf2O

N-sulfonylpyrrolidines and N-alkyl sulfonamides were efficiently prepared via alkylation of sulfonamides with 1,4- diols or alcohols by Tf2O. The reaction occurred under mild reaction conditions in moderate to high yields and tolerated aryl and aliphatic sulfonamides.

TRICYCLIC ALKYNES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN

The present invention relates to tricyclic alkyne compounds of formula I that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diabetes, and other diseases and/or conditions where gluco