198573-86-3 Usage
Description
(R)-BIPHENYL-(3,4-DIMETHYL-1-CYCLOPENTADIENYL)-TITANIUM(IV)-(R)-1,1'-BINAPHTHYL-2, also known as Ti-BINAP, is a metal complex used in organic chemistry as a catalyst. It consists of a titanium atom coordinated with a cyclopentadienyl ligand and a binaphthyl ligand. This complex is commonly employed in asymmetric synthesis reactions, where it acts as a chiral catalyst to facilitate the formation of stereochemically pure products. Ti-BINAP has shown high activity and selectivity in various catalytic reactions, making it a valuable tool for the synthesis of pharmaceuticals, agrochemicals, and other complex organic compounds.
Uses
Used in Pharmaceutical Industry:
Ti-BINAP is used as a chiral catalyst for the synthesis of pharmaceuticals, as it helps in the production of stereochemically pure compounds. Its high activity and selectivity make it a valuable tool in creating the desired enantiomers of drugs, which can have significant effects on the efficacy and safety of the final product.
Used in Agrochemical Industry:
In the agrochemical industry, Ti-BINAP is used as a catalyst for the production of various agrochemicals. Its ability to facilitate asymmetric synthesis reactions allows for the creation of specific enantiomers of pesticides and other agrochemicals, which can be more effective and have fewer side effects on the environment and non-target organisms.
Used in Organic Synthesis:
Ti-BINAP is also used in organic synthesis for the creation of complex organic compounds. Its role as a chiral catalyst enables the production of specific enantiomers of target molecules, which can be crucial in the development of new materials, fragrances, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 198573-86-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,8,5,7 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 198573-86:
(8*1)+(7*9)+(6*8)+(5*5)+(4*7)+(3*3)+(2*8)+(1*6)=203
203 % 10 = 3
So 198573-86-3 is a valid CAS Registry Number.
198573-86-3Relevant articles and documents
Asymmetric thermal transformation, a new way to enantiopure biphenyl- bridged titanocene and zirconocene complexes: Efficient catalysts for asymmetric imine hydrogenation
Ringwald, Markus,Stürmer, Rainer,Brintzinger, Hans H.
, p. 1524 - 1527 (2007/10/03)
Enantiopure biphenyl-bridged titanocene and zirconocene complexes were obtained, by an asymmetric thermal transformation of the binaphthol complexes formed from the metallocene racemates and subsequent transformation to the corresponding dichlorides, in practically quantitative yields. Increased rates of this transformation in the presence of O2 gas or TEMPO indicate a radical reaction mechanism. The biphenyl-bridged titanocene enantiomers give rise to an efficient asymmetric catalysis for the hydrogenation of cyclic and noncyclic imines.
