19875-04-8 Usage
Description
4(1H)-Pyrimidinone, 2-methyl(8CI,9CI), also known as 4-Hydroxy-2-methylpyrimidine, is an organic compound that serves as a valuable synthetic intermediate in the chemical and pharmaceutical industries. It is characterized by its unique molecular structure, which features a pyrimidine ring with a methyl group and a hydroxyl group at the 2nd and 4th positions, respectively.
Uses
Used in Pharmaceutical Industry:
4(1H)-Pyrimidinone, 2-methyl(8CI,9CI) is used as a synthetic intermediate for the development of various pharmaceutical compounds. It plays a crucial role in the synthesis of 2-Methyl-4-pyrimidinyl-boronic Acid (M328125), which is further utilized in the production of indazole-derived S-adenosyl homocysteine/methylthioadenosine nucleosidase inhibitors. These inhibitors possess potent antimicrobial activities, making them valuable in the development of new antibiotics and antifungal agents to combat drug-resistant infections.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4(1H)-Pyrimidinone, 2-methyl(8CI,9CI) serves as a key building block for the creation of a wide range of complex organic molecules. Its unique structure allows for various functional group transformations and reactions, enabling the synthesis of diverse compounds with potential applications in various industries, such as agrochemicals, dyes, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 19875-04-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,8,7 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19875-04:
(7*1)+(6*9)+(5*8)+(4*7)+(3*5)+(2*0)+(1*4)=148
148 % 10 = 8
So 19875-04-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N2O/c1-4-6-3-2-5(8)7-4/h2-3H,1H3,(H,6,7,8)
19875-04-8Relevant articles and documents
Novel pyrimidine nucleoside oxosulfonium ylides and their photolysis to 2,2'-methylenecyclonucleosides.
Kunieda,Witkop
, p. 7752 - 7754 (1969)
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ANTIVIRAL AGENT
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Page 168, (2010/02/06)
The present invention provides an integrase inhibitor. The inventors have have found the following compound of formula (I) possessing an integrase inhibitory activity. (wherein, R C and R D taken together with the neighboring carbon atoms form a ring which may be a condensed ring, Y is hydroxy, mercapto or amino; Z is O, S or NH ; R A is a group shown by (wherein, C ring is N-containing aromatic heterocycle) or the like)
PIPERAZINE SUBSTITUTED PYRIMIDINE DERIVATIVES AND PHYSIOLOGICALLY TOLERATED SALTS THEREOF
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, (2008/06/13)
Pyrimidine derivatives of the formula I I in which R1, R2, R3, R4 and R5 have the indicated meanings, the salts thereof, and a process for the preparation thereof are described. Because of their sorbitol-accumulating activity, they are suitable as a tool in a pharmacological screening model for aldose reductase inhibitors
