19895-34-2

Basic information

• Product Name: 5,6-dihydro-6,6-dimethyl-2H-pyran-2-one
• Synonyms: 5,6-dihydro-6,6-dimethyl-2H-pyran-2-one
• CAS NO: 19895-34-2
• Molecular Weight: 126.155
• Mol File: 19895-34-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,6-dihydro-6,6-dimethyl-2H-pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-dihydro-6,6-dimethyl-2H-pyran-2-one(19895-34-2)
• EPA Substance Registry System: 5,6-dihydro-6,6-dimethyl-2H-pyran-2-one(19895-34-2)

Safety Data

• Hazardous Substances Data: 19895-34-2(Hazardous Substances Data)

Upstream product

• 13831-03-3 tert-butyl prop-2-ynoate 
• 766-90-5 cis-1-phenyl-1-propylene 

Downstream Products

• 79559-18-5 tetrahydro-4-anilino-6,6-dimethyl-2H-pyran-2-one 
• 82027-10-9 2'-(phenylseleno)dihydrocatalpalactone 
• 1585-68-8 catalpalactone 
• 2610-95-9 6,6-dimethyltetrahydro-2H-pyran-2-one 

Relevant articles and documents

Asymmetric Synthesis of Dihydropyranones via Gold(I)-Catalyzed Intermolecular [4+2] Annulation of Propiolates and Alkenes

Intermolecular asymmetric gold catalysis involving alkyne activation presents a significant challenge due to its distinct mechanistic mode from other metals. Herein, we report a highly enantioselective synthesis of α,β-unsaturated δ-lactones from [4+2] annulation of propiolates and alkenes in upto 95 percent ee. Notably, for the desired chiral recognition, the choice of 1,1,2,2-tetrachloroethane as solvent was found to be crucial. Furthermore, an anionic surfactant (sodium dodecyl sulfate) improved the product selectivity in the divergence of the cyclopropyl gold carbene intermediate.