199188-36-8Relevant articles and documents
Vicinal Difunctionalization of Alkenes Using Vinyl Triflates Leading to γ-Trifluoromethylated Ketones
Kawamoto, Takuji,Kawabata, Takahiro,Noguchi, Kohki,Kamimura, Akio
supporting information, p. 324 - 327 (2022/01/04)
We report a new methodology for the synthesis of γ-trifluoromethylated ketones from alkenes and vinyl triflate bifunctional reagents. The reaction proceeds via the addition of a β-trifluoromethyl alkyl radical to a vinyl triflate, followed by β-cleavage.
BEXAROTENE DERIVATIVES AND THEIR USE IN TREATING CANCER
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Paragraph 0120, (2019/09/18)
This disclosure relates to compositions and methods for treating cancer. Specifically, this disclosure relates to bexarotene derivatives, methods for treating cancer, autoimmune disorders, and/or skin dermatitis, and/or methods for increasing peripheral blood counts and/or improving immune system function.
Visible light induced Trifluoromethyl Migration: Easy Access to α-Trifluoromethylated Ketones from Enol Triflates
Liu, Shuyang,Jie, Jiyang,Yu, Jipan,Yang, Xiaobo
supporting information, p. 267 - 271 (2017/11/13)
Herein, we reported a novel method to synthesize α-trifluoromethylated ketones from enol triflates. Involving a cascade sulfur dioxide extrusion and a CF3 (trifluoromethyl) radical addition process, this reaction proceeds at room temperature an
