199445-85-7Relevant articles and documents
Tandem hydroformylation-acetalization of para-menthenic terpenes under non-acidic conditions
Vieira, Camila G.,Da Silva, José G.,Penna, Cristiano A. A.,Dos Santos, Eduardo N.,Gusevskaya, Elena V.
, p. 125 - 132 (2010)
Rhodium-catalyzed tandem hydroformylation/acetalization of a series of para-menthenic terpenes, i.e., α-terpinene (1), γ-terpinene (2), terpinolene (3), and limonene (4), has been studied in ethanol solutions in the presence Of PPh3 or P(O-o-s
An efficient method for the transformation of naturally occurring monoterpenes into amines through rhodium-catalyzed hydroaminomethylation
Melo, Daniela S.,Pereira-Júnior, Schubert S.,Dos Santos, Eduardo N.
experimental part, p. 70 - 76 (2012/03/22)
The hydroaminomethylation (hydroformylation/reductive amination) of the naturally occurring monoterpenes, i.e., limonene, camphene, and β-pinene, was studied having as condensation counterparts the amines di-n-butylamine, morpholine or n-butylamine. Moderate to good yields (75-94%) were obtained employing [Rh(cod)(μ-OMe)]2 as pre-catalyst in the presence or not of triphenylphosphine or tribenzylphosphine as ancillaries in toluene, at 100 °C and 60 bar of an equimolar mixture of carbon monoxide and hydrogen. Some of the hydroaminomethylation products derived from limonene have biological activity and the products derived from camphene and β-pinene are new.
Synthesis and in vitro activity of limonene derivatives against Leishmania and Trypanosoma
Graebin, Cedric S.,Madeira, Maria de F.,Yokoyama-Yasunaka, Jenicer K.U.,Miguel, Danilo C.,Uliana, Silvia R.B.,Benitez, Diego,Cerecetto, Hugo,González, Mercedes,Rosa, Ricardo Gomes da,Eifler-Lima, Vera Lucia
scheme or table, p. 1524 - 1528 (2010/06/14)
The synthesis and in vitro activity of R(+)-Limonene derivatives against Leishmania and Trypanosoma cruzi strains are reported. Seven compounds have shown better in vitro activity against Leishmania (V.)braziliensis than the standard drug pentamidine. Add
