199611-77-3

Basic information

• Product Name: 1,2-dihydro-6-(3-cyano-5-fluorophenyl)-2,2,4-trimethyl-1-t-butoxycarbonylquinoline
• Synonyms: 1,2-dihydro-6-(3-cyano-5-fluorophenyl)-2,2,4-trimethyl-1-t-butoxycarbonylquinoline
• CAS NO: 199611-77-3
• Molecular Weight: 392.473
• Mol File: 199611-77-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-dihydro-6-(3-cyano-5-fluorophenyl)-2,2,4-trimethyl-1-t-butoxycarbonylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dihydro-6-(3-cyano-5-fluorophenyl)-2,2,4-trimethyl-1-t-butoxycarbonylquinoline(199611-77-3)
• EPA Substance Registry System: 1,2-dihydro-6-(3-cyano-5-fluorophenyl)-2,2,4-trimethyl-1-t-butoxycarbonylquinoline(199611-77-3)

Safety Data

• Hazardous Substances Data: 199611-77-3(Hazardous Substances Data)

Upstream product

• 1435-51-4 1,3-dibromo-5-fluorobenzene 
• 179898-34-1 3-bromo-5-fluorobenzonitrile 
• 179894-36-1 (1-tert-butyloxycarbonyl-1,2-dihydro-2,2,4-trimethyl-6-quinolinyl)boronic acid 

Downstream Products

• 179896-18-5 6-(3-Cyano-5-fluorophenyl)-1,2-dihydro-2,2,4-trimethyl-3-quinolone 
• 179896-03-8 LG120830 

Relevant articles and documents

Discovery and preliminary SAR studies of a novel, nonsteroidal progesterone receptor antagonist pharmacophore

A series of 6-aryl-1,2-dihydro-2,2,4-trimethylquinolines was synthesized and tested for functional activity on the human progesterone receptor isoform B (hPR-B) in mammalian (CV-1) cells. The lead compound LG001447 (1,2-dihydro- 2,2,4-trimethyl-6-phenylqu