199680-59-6Relevant articles and documents
Synthesis and structure-activity relationships of 3,7-dimethyl-1- propargylxanthine derivatives, A(2A)-selective adenosine receptor antagonists
Müller, Christa E.,Geis, Uli,Hipp, Jo,Schobert, Ulrike,Frobenius, Wolfram,Paw?owski, Maciej,Suzuki, Fumio,Sandoval-Ramírez, Jesús
, p. 4396 - 4405 (2007/10/03)
A series of 8-substituted derivatives of 3,7-dimethyl-1- propargylxanthine (DMPX) was synthesized and investigated as A(2A) adenosine receptor antagonists. Different synthetic strategies for the preparation of DMPX derivatives and analogues were explored.