199742-72-8

Basic information

• Product Name: 1-[2-bromo-4,5-dimethoxybenzyl]-2-[((1S,2R)-(1-methyl-1-phenylethyl)cyclohexyloxy)carbonyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 1-[2-bromo-4,5-dimethoxybenzyl]-2-[((1S,2R)-(1-methyl-1-phenylethyl)cyclohexyloxy)carbonyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 199742-72-8
• Molecular Weight: 666.652
• Mol File: 199742-72-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[2-bromo-4,5-dimethoxybenzyl]-2-[((1S,2R)-(1-methyl-1-phenylethyl)cyclohexyloxy)carbonyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-bromo-4,5-dimethoxybenzyl]-2-[((1S,2R)-(1-methyl-1-phenylethyl)cyclohexyloxy)carbonyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline(199742-72-8)
• EPA Substance Registry System: 1-[2-bromo-4,5-dimethoxybenzyl]-2-[((1S,2R)-(1-methyl-1-phenylethyl)cyclohexyloxy)carbonyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline(199742-72-8)

Safety Data

• Hazardous Substances Data: 199742-72-8(Hazardous Substances Data)

Upstream product

• 161693-64-7 (1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl chloroformate 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 199742-71-7 N-[(1S,2R)-(2-(1-methyl-1-phenylethyl)cyclohexyloxy)carbonyl]-2-(3,4-dimethoxyphenyl)ethylamine 

Downstream Products

• 523-02-4 (S)-(-)-norcoralydine 
• 109527-45-9 (1S,2R)-(+)-trans-2-(1-methyl-1-phenylethyl)cyclohexanol 
• 79703-32-5 (S)-(-)-2,3,10,11-tetramethoxy-5,6,13,13a-tetrahydroisoquino[3,2-a]isoquinolin-8-one 

Relevant articles and documents

Chiral auxiliary mediated pictet-spengler reactions: Asymmetric syntheses of (-)-laudanosine, (+)-glaucine and (-)-xylopinine

Cyclohexyl-based chiral auxiliaries can be used effectively in an asymmetric Pictet-Spengler synthesis of tetrahydroisoquinoline, aporphine and protoberbine alkaloids. Using this strategy, concise asymmetric syntheses of (-)-laudanosine, (+)-glaucine and (+)- xylopinine have been accomplished.