19989-69-6Relevant articles and documents
Method used for rapid preparation of benzo-heterocycle compound with physical grinding under solvent-free room temperature conditions
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Paragraph 0062; 0171, (2019/01/21)
The invention discloses a method used for rapid preparation of benzo-heterocycle compound with physical grinding under solvent-free room temperature conditions. According to the method, glacial aceticacid is taken as a catalyst; at solvent-free room temperature conditions, physical grinding is adopted, reaction of 2-substituted arylamines (2-mercapto arylamine, 2-aminophenol, and o-phenylenediamine) and aromatic aldehydes is carried out using physical grinding. The method is friendly to the environment, is simple in operation, is safe, is low in cost, and is high in efficiency. Compared withthe prior art, the advantages are that: the method is suitable for a large amount of functional groups, yield is high, less by-product is generated, operation is simple, the method is safe, cost is low, and the method is friendly to the environment.
OXOPIPERAZINE-AZETIDINE AMIDES AND OXODIAZEPINE-AZETIDINE AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS
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Page/Page column 35, (2012/04/05)
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds, and enantiomers, diastereomers, and pharmaceutically acceptable salts thereof, are represented by Formula (Ia) and Formula (Ib) as follows: wherein Y, Z, and n are defined herein; and wherein Yb and Zb are as defined herein.
Microwave-assisted syntheses of 2-phenylbenzothiazoles
Pal, Sudhir,Patra, Gopal,Bhunia, Sankar
experimental part, p. 1196 - 1203 (2009/10/09)
A new and easy synthetic route to 2-phenylbenzothiazoles has been achieved by direct thiation of benzoyl derivatives of aniline, various substituted anilines, and 1-naphthylamine under microwave irradiation. The oxidative cyclization using elemental sulfur in the presence of a catalytic amount of iodine is inexpensive and worked well for a number of anilides. Copyright Taylor & Francis Group, LLC.