199990-65-3

Basic information

• Product Name: 4-{5-Ethyl-4-[3-(2-ethyl-octylamino)-benzoyl]-1-methyl-1H-pyrrol-2-yl}-butyric acid ethyl ester
• CAS NO: 199990-65-3
• Molecular Weight: 482.707
• Mol File: 199990-65-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{5-Ethyl-4-[3-(2-ethyl-octylamino)-benzoyl]-1-methyl-1H-pyrrol-2-yl}-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{5-Ethyl-4-[3-(2-ethyl-octylamino)-benzoyl]-1-methyl-1H-pyrrol-2-yl}-butyric acid ethyl ester(199990-65-3)
• EPA Substance Registry System: 4-{5-Ethyl-4-[3-(2-ethyl-octylamino)-benzoyl]-1-methyl-1H-pyrrol-2-yl}-butyric acid ethyl ester(199990-65-3)

Safety Data

• Hazardous Substances Data: 199990-65-3(Hazardous Substances Data)

Upstream product

• 20592-10-3 2-ethyloctane-1-ol 
• 37596-38-6 2-ethyl-octanal 
• 25234-28-0 1-bromo-2-ethyloctane 
• 199989-55-4 4-[4-(3-Benzyloxycarbonylamino-benzoyl)-5-ethyl-1-methyl-1H-pyrrol-2-yl]-butyric acid ethyl ester 
• 199989-50-9 (E)-4-[5-Ethyl-1-methyl-4-(3-nitro-benzoyl)-1H-pyrrol-2-yl]-but-2-enoic acid ethyl ester 
• 199989-51-0 4-[4-(3-Amino-benzoyl)-5-ethyl-1-methyl-1H-pyrrol-2-yl]-butyric acid ethyl ester 
• 199995-81-8 5-Ethyl-1-methyl-4-(3-nitro-benzoyl)-1H-pyrrole-2-carbaldehyde 
• 199995-80-7 5-Ethyl-4-(3-nitro-benzoyl)-1H-pyrrole-2-carbaldehyde 
• 121-90-4 m-nitrobenzoic acid chloride 
• 925-78-0 3-nonanone 
• 1551-06-0 2-ethyl-1H-pyrrole 

Relevant articles and documents

Pyrrole butyric acid derivatives as inhibitors of steroid 5α- reductase

A series of pyrrole butyric acid derivatives was synthesized and evaluated for inhibitory activity on human and rat steroid 5α-reductase in vitro and ex vivo. 3-Benzoyl-4-alkylpyrrole-1-butyric acids and 1-methyl- 2-alkyl-3-benzoylpyrrole-5-butyric acid derivatives were effective inhibitors. Structure activity relationships were evaluated among the 37 compounds synthesized. Compound 37 (HQL-1069) shows potent inhibitory activities against both rat and human 5α-reductase.