199991-84-9

Basic information

• Product Name: C₃₆H₄₆O₈
• Synonyms: C₃₆H₄₆O₈
• CAS NO: 199991-84-9
• Molecular Weight: 606.756
• Mol File: 199991-84-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₃₆H₄₆O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₆H₄₆O₈(199991-84-9)
• EPA Substance Registry System: C₃₆H₄₆O₈(199991-84-9)

Safety Data

• Hazardous Substances Data: 199991-84-9(Hazardous Substances Data)

Upstream product

• 72652-35-8 1,3-bis-bromomethyl-2,5-dimethoxy-benzene 
• 94199-20-9 (S)-(+)-2-phenyl-2-(tetrahydropyranyloxy)ethanol 

Downstream Products

• 188303-41-5 (5S,8S,10S,13S)-19,21-Dimethoxy-8,10-dimethyl-5,13-diphenyl-3,6,9,12,15-pentaoxa-bicyclo[15.3.1]henicosa-1⁽²⁰⁾,17⁽²¹⁾,18-triene 
• 188303-42-6 (5S,8S,10S,13S)-19-Methoxy-8,10-dimethyl-5,13-diphenyl-3,6,9,12,15-pentaoxa-bicyclo[15.3.1]henicosa-1⁽²⁰⁾,17⁽²¹⁾,18-trien-21-ol 
• 199992-19-3 (5S,8S,10S,13S)-8,10-Dimethyl-5,13-diphenyl-3,6,9,12,15-pentaoxa-bicyclo[15.3.1]henicosa-1⁽²⁰⁾,17-diene-19,21-dione 
• 209622-58-2 (5S,13S)-19,21-Dimethoxy-5,13-diphenyl-3,6,9,12,15-pentaoxa-bicyclo[15.3.1]henicosa-1⁽²⁰⁾,17⁽²¹⁾,18-triene 
• 209622-59-3 (5S,13S)-19-Methoxy-5,13-diphenyl-3,6,9,12,15-pentaoxa-bicyclo[15.3.1]henicosa-1⁽²⁰⁾,17⁽²¹⁾,18-trien-21-ol 
• 188303-40-4 (S)-2-[3-((S)-2-Hydroxy-2-phenyl-ethoxymethyl)-2,5-dimethoxy-benzyloxy]-1-phenyl-ethanol 

Relevant articles and documents

Preparation and temperature-dependent enantioselectivities of homochiral phenolic crown ethers having aryl chiral barriers: Thermodynamic parameters for enantioselective complexation with chiral amines

Homochiral crown ether (S,S)-1 containing 1-naphthyl groups as chiral barriers together with the phenol moiety was prepared by using (S)-3 as a chiral subunit which was resolved in enantiomerically pure form by lipase- catalyzed enantioselective acylation of (±)-3. Homochiral phenolic crown ether (S,S)-2, containing phenyl groups as chiral barriers, was also prepared from (S)-5 which was derived from (S)-mandelic acid. The association constants for their complexes with chiral amines in CHCl3 were determined at various temperatures by the UV-visible spectroscopic method demonstrating that the crown ethers (S,S)-1 and (S,S)-2 displayed the large Δ(R)-(S)ΔG values of 6.2 and 6.4 kJ mol-1, respectively, towards the amine 21 at 15°C. Thermodynamic parameters for complex formation were also determined and a linear correlation between TΔ(R-S)ΔS and Δ(R-S)ΔH values was observed.

Preparation of homochiral azophenolic crown ethers containing 1-phenylethane-1,2-diol and 2,4-dimethyl-3-oxapentane-1,5-diol as a chiral subunit: Enantiomer recognition behaviour towards chiral 2-aminoethanol derivatives

Enantiomerically pure azophenolic crown ethers 1-4 containing (S)- or (R)-1-phenylethane-1,2-diol moieties and (2S,4S)-2,4-dimethyl-3-oxapentane-1,5-diol moiety as a chiral subunit were prepared; crown ethers (S,S,S,S)-1 showed high chiral recognition behaviour in complexation with 2-substituted 2-aminoethanol derivatives.