200204-85-9

Basic information

• Product Name: ethyl 2-(5-bromobenzofuran-3-yl)acetate
• Synonyms: 5-bromo-3-Benzofuranacetic acid ethyl ester;Ethyl 2-(5-bromobenzofuran-3-yl);ethyl 2-(5-bromobenzofuran-3-yl)acetate
• CAS NO: 200204-85-9
• Molecular Formula: C12H11BrO3
• Molecular Weight: 283.12
• Product Categories: CHIRAL CHEMICALS
• Mol File: 200204-85-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 341.683 °C at 760 mmHg
• Flash Point: 160.445 °C
• Appearance: /
• Density: 1.476 g/cm³
• Vapor Pressure: 7.91E-05mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ethyl 2-(5-bromobenzofuran-3-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(5-bromobenzofuran-3-yl)acetate(200204-85-9)
• EPA Substance Registry System: ethyl 2-(5-bromobenzofuran-3-yl)acetate(200204-85-9)

Safety Data

• Hazardous Substances Data: 200204-85-9(Hazardous Substances Data)

Usage

General Description

Ethyl 2-(5-bromobenzofuran-3-yl)acetate is a chemical compound with the molecular formula C12H11BrO3. It is a derivative of benzofuran, a heterocyclic compound with a furan ring fused to a benzene ring, and it contains an ethyl ester and a bromine functional group. ethyl 2-(5-bromobenzofuran-3-yl)acetate is commonly used in the synthesis of pharmaceuticals and agrochemicals. Its properties and reactivity make it valuable in organic chemistry research and development. The precise applications of ethyl 2-(5-bromobenzofuran-3-yl)acetate depend on its particular structural features and the intended reaction or use in a specific process or compound.

InChI:InChI=1/C12H11BrO3/c1-2-15-12(14)5-8-7-16-11-4-3-9(13)6-10(8)11/h3-4,6-7H,2,5H2,1H3

Upstream product

• 54450-20-3 5-bromo-3(2H)-benzofuranone 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 106-41-2 4-bromo-phenol 
• 100959-21-5 2-hydroxy-5-bromophenacyl chloride 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 64-17-5 ethanol 

Relevant articles and documents

Synthesis and preliminary evaluation of benzofuran-oxadiazole conjugates as potential antitubercular agents

In the present study, a series of benzofuran-oxadiazole conjugates 7(a-o) was designed, synthesized and characterized through IR,1H NMR,13C NMR and mass spectral data. All the compounds were screened for preliminary antitubercular activity against Mycobacterium phlei and Mycobacterium tuberculosis H37RV. Among all the target compounds, the compound possessing chlorine (7k, MIC 1.56 μg/mL) and bromine (7m, MIC 1.56 μg/mL) on 6th position of benzofuran showed highest activity against Mycobacterium phlei. Whereas, bromine on either 5th position (7l, MIC 3.125 μg/mL) or 6th position (7m MIC 3.125 μg/mL) on benzofuran exhibited highest activity for Mycobacterium tuberculosis (H37 RV).

Azetidine, pyrrolidine and piperidine derivatives as 5-HT1D receptor agonists

PCT No. PCT/GB97/01330 Sec. 371 Date Oct. 26, 1998 Sec. 102(e) Date Oct. 26, 1998 PCT Filed May 15, 1997 PCT Pub. No. WO97/45426 PCT Pub. Date Dec. 4, 1997A class of substituted azetidine, pyrrolidine and piperidine derivatives of Formula I are selective