2003-82-9

Basic information

• Product Name: 1-bromoprop-1-yne
• Synonyms: 1-Bromoprop-1-yne; 1-propyne, 1-bromo-; Propyne, 1-bromo-; Propynyl bromide
• CAS NO: 2003-82-9
• Molecular Formula: C₃H₃Br
• Molecular Weight: 118.9599
• Mol File: 2003-82-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 77°C at 760 mmHg
• Flash Point: 6.2°C
• Density: 1.595g/cm³
• Vapor Pressure: 108mmHg at 25°C
• Refractive Index: 1.493
• CAS DataBase Reference: 1-bromoprop-1-yne(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromoprop-1-yne(2003-82-9)
• EPA Substance Registry System: 1-bromoprop-1-yne(2003-82-9)

Safety Data

• Hazardous Substances Data: 2003-82-9(Hazardous Substances Data)

Usage

General Description

1-Bromoprop-1-yne, also known as 1-Bromo-1-propyne, is a chemical compound with the molecular formula C3H3Br. It is a colorless liquid with a sharp, sweet odor, and it is mainly used in organic synthesis as a building block for the preparation of various compounds. It is a highly reactive compound due to the presence of both a bromine and a triple bond, making it prone to undergo addition reactions with nucleophiles. Additionally, 1-Bromoprop-1-yne is also used in the production of pharmaceuticals, agrochemicals, and in the manufacturing of rubber and plastic products. However, it is important to handle this chemical with caution as it is toxic and flammable, and proper safety measures should be taken when working with it.

Upstream product

• 14602-62-1 1,1,2-tribromo-propane 
• 74-99-7 prop-1-yne 
• 7726-95-6 bromine 
• 53210-70-1 silver(I) propynyde 
• 13195-80-7 1,1-dibromopropene 

Downstream Products

• 74-99-7 prop-1-yne 
• 100374-41-2 1-ethynyl-4-penta-1,3-diynyl-cyclohexa-2,5-diene-1,4-diol 
• 101277-95-6 1,4-di-penta-1,3-diynyl-cyclohexa-2,5-diene-1r,4t-diol 
• 101736-41-8 1,1-diphenyl-hexa-2,4-diyn-1-ol 
• 1595-67-1 1-<4-Chlor-phenyl>-hexadiin-(2,4)-ol-(1) 
• 1595-65-9 1-p-Methoxyphenylhexa-2,4-di-in-1-ol 
• 1595-58-0 1-p-Dimethylaminophenylhexa-2,4-di-in-1-ol 
• 1595-57-9 1-p-Carboxyphenylhexa-2,4-di-in-1-ol 
• 15375-63-0 1-Diphenylamino-hexadiin-(2.4) 
• 4009-22-7 agropyrene 
• 1574-95-4 1-phenyl-2,4-hexadiyn-1-ol 
• 127357-38-4 N-(benzyloxycarbonyl)-α-hydroxy-glycine methyl ester 
• 119839-50-8 methyl 2-amino-N-(benzyloxycarbonyl)-3-pentynoate 
• 126403-76-7 2-Amino-3-prop-1-ynyl-benzonitrile 

Relevant articles and documents

The Hexadehydro-Diels-Alder Cycloisomerization Reaction Proceeds by a Stepwise Mechanism

We report here experiments showing that the hexadehydro-Diels-Alder (HDDA) cycloisomerization reaction proceeds in a stepwise manner - i.e., via a diradical intermediate. Judicious use of substituent effects was decisive. We prepared (i) a series of triyn

Practical and safe procedures for the preparation of the lower homologues of bromoacetylene

The lower homologues of bromoacetylene, from 1-bromopropyne to 1-bromo-1-hexyne, have been prepared in excellent yield by stirring the alkyne (in the cases of 1-propyne and 1-butyne a dilute solution in high-boiling petroleum ether) with a very concentrated aqueous solution of potassium hypobromite and potassium hydroxide.

Reactions of HDDA-Derived Benzynes with Sulfides: Mechanism, Modes, and Three-Component Reactions

We report here reactions of alkyl sulfides with benzynes thermally generated by the hexadehydro-Diels-Alder (HDDA) cycloisomerization. The initially produced 1,3-betaine (o-sulfonium/aryl carbanion) undergoes intramolecular proton transfer to generate a more stable S-aryl sulfur ylide. This can react in various manners, including engaging weak acids (HA) in the reaction medium. This can produce transient ion pairs ArSR2+A- that proceed to the products ArSR + RA. When cyclic sulfides are used, A- opens the ring and is incorporated into the product, an outcome that constitutes a versatile, three-component coupling process.