20030-09-5Relevant articles and documents
Mucohalic acid in Lewis acid catalyzed Mukaiyama aldol reaction: A concise method for highly functionalized γ-substituted γ-butenolides
Angell, Paul,Zhang, Ji,Belmont, Daniel,Curran, Timothy,Davidson, James G.
, p. 2029 - 2032 (2005)
The first Mukaiyama aldol reaction on mucohalic acid (1a/b) has been achieved. Reaction of 1 with various ketene silyl acetals or silyl enol ethers in the presence of a Lewis acid provides the γ-substituted γ-butenolides in good to excellent yield.